Lactobacillus plantarum as Next Generation Probiotics
Background L. plantarum and Diseases Products Brochures FAQs Resources
Lactobacillus plantarum is a class of normal gut microflora that utilizes carbon sources to produce lactic acid, ethanol or acetic acid, and carbon dioxide. In the food industry, L. plantarum is a fermentative bacterium, commonly found in sauerkraut, pickles, brined olives, Korean kimchi, etc. Besides, L. plantarum is a promising probiotic for diarrhea, high cholesterol, and atopic dermatitis.
Creative Biolabs has accumulated a great deal of experience in the development of next-generation probiotics. We offer a full range of services with high quality to advance L. plantarum probiotics development, including identification and isolation of L. plantarum, safety test for L. plantarum probiotics, host-microbe interaction test, and L. plantarum probiotics cGMP manufacturing.
Introduction of L. plantarum
L. plantarum, belonging to the genus Lactobacillus, is a type of anaerobic gram-positive microorganisms. It is widespread and commonly found in many foods and feeds, such as dairy, meat, fish, must, pickled vegetables, sauerkraut, sourdoughs, and silage. It is also a natural resident of the human and animal mucosa, including the oral cavity, gastrointestinal tract, vagina. L. plantarum cells are rod-shaped with a rounded end, generally, 0.9-1.2 μm wide and 3-8 μm long, occurring singly, in pairs, or short chains. L. plantarum is a resilient and highly adaptive bacteria that can grow at temperatures between 12-40 ℃ and at pH level between 3.4-8.8. It uses carbon sources to produce lactic acid, ethanol or acetic acid, and carbon dioxide. It represents a part of the microbiota of many fermented foods. It is also considered as promising next-generation probiotics since it has anti-cancer, anti-inflammatory, antiobesity, and antidiabetic properties.
Potential of L. plantarum Probiotics for Disease Treatment
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Diseases
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Functions of L. plantarum
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Diarrhea
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Lactobacillus probiotics have been reported to have great potential for relieving antibiotic-associated diarrhea. L. plantarum probiotics can reduce the occurrence of loose or watery stools and abdominal pain without negative side effects in a clinical trial of 438 children with antibiotic-associated diarrhea.
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Skin Health
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L. plantarum has been shown to improve skin hydration, promote the synthesis of collagen, and decrease reactive oxygen species (ROS) production. It may act as an anti-aging agent used for skin health care. Furthermore, L. plantarum has also been shown to relieve the symptoms of atopic dermatitis in humans.
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Reducing Cholesterol
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Several clinical trials have reported that L. plantarum probiotics can reduce cholesterol. In a research of 60 individuals with high cholesterol, L. plantarum probiotics decrease total cholesterol by 13.6%. In mice with elevated cholesterol, L. plantarum can significantly reduce total serum cholesterol and triglycerides.
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Obesity
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Many studies showed L. plantarum can lower body weight and fat mass in humans and mice. In Russian adults with obesity and hypertension, a probiotic-enriched cheese containing L. plantarum reduced the BMI and blood pressure. Besides, L. plantarum also reduces diet-induced obesity in mice.
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Diabetes Mellitus
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L. plantarum has been shown to decrease the level of blood glucose. In mice with a high-fat diet, L. plantarum can significantly reduce blood glucose levels in response to insulin. In the diabetic rats, ingestion of L. plantarum probiotics can also reduce blood glucose and hormones, and increase lipid metabolism.
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Related Products
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Product Name
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Product Overview
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Price
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LBP-004CYG
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Lactobacillus plantarum Powder
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Freeze-dried L. plantarum Powder
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Inquiry
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LBST-131FG
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Lactobacillus plantarum; 1.191
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L. plantarum cells are rods with rounded ends. They are homofermentative, aerotolerant Gram-positive bacteria.
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Inquiry
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LBST-132FG
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Lactobacillus plantarum subsp. plantarum; Fermented yak milk
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Bacteria from the L. plantarum species are typically gram positive, non-spore-forming, and rod-shaped, occurring both singly or grouped together in short chains.
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Inquiry
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LBST-133FG
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Lactobacillus plantarum subsp. plantarum; 20022
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Bacteria from the L. plantarum species are typically gram positive, non-spore-forming, and rod-shaped, occurring both singly or grouped together in short chains.
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Inquiry
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LBGF-0722-GF85
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Lactobacillus plantarum subsp. plantarum; 20174
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Bacteria from the L. plantarum species are typically Gram-positive, non-spore-forming, and rod-shaped, occurring both singly or grouped together in short chains.
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Inquiry
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LBGF-0224-GF5
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Lactobacillus plantarum DNA Standard
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L. plantarum DNA standard product can be used for quantitative research and analysis, assay development, verification, and validation, and laboratory quality control.
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Inquiry
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LBGF-0224-GF36
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Heat inactivated Lactobacillus plantarum
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L. plantarum has been inactivated by heating to 65°C for 30 minutes.
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Inquiry
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With the continuous research and understanding of L. plantarum, it is possible to develop L. plantarum probiotics for improving health. To date, we have successfully finished several projects related to next-generation probiotics development and accumulated rich experience. We are confident in offering all-rounded L. plantarum probiotics development services for global customers from program design, implementation to data analysis. We are expected to become your reliable partner in the field of next-generation probiotics development. Please hesitate to contact us to discuss your project.
Brochures
FAQs
What are the key benefits of using L. plantarum as a next-generation probiotic in research?
L. plantarum is recognized for its versatility in various applications, including gut health, immune modulation, and antimicrobial properties. This bacterium is also resilient to different environmental conditions, making it ideal for experimental studies focused on improving health and understanding probiotic functions.
What advantages does L. plantarum offer in immunomodulation research?
L. plantarum is known for its ability to influence the immune system by enhancing both innate and adaptive immune responses. This makes it an excellent candidate for studies focusing on immune modulation, vaccine development, and anti-inflammatory research.
Can L. plantarum be used in antimicrobial research?
Yes, L. plantarum has demonstrated antimicrobial activities against a variety of pathogens, including harmful bacteria and fungi. Its use in research can help develop novel antimicrobial agents and explore the mechanisms behind its inhibitory effects.
What makes L. plantarum a preferred choice for non-clinical research services?
L. plantarum is a robust and well-documented probiotic with a wide range of health benefits. Its extensive use in non-clinical research services is supported by its proven efficacy, safety profile, and adaptability to various experimental setups, providing researchers with reliable and consistent results.
Resources
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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