For L. paracasei, we isolate target strains from traditional fermented foods (e.g., yogurt, cheese) and/or human gut-derived samples using selective workflows, then run high-throughput screening for acid tolerance, bile tolerance, and other performance-linked traits to shortlist strains with real commercial potential.
We confirm whether your isolate is truly L. paracasei using a layered identity strategy—16S rRNA sequencing, whole-genome sequencing (WGS), and biochemical profiling—then map phylogeny and relatedness to ensure traceable genetic background, clean lineage, and defensible strain documentation.
We evaluate L. paracasei functional signatures including lactic acid production, antimicrobial activity (including bacteriocin-associated effects), antioxidant capacity, and epithelial adhesion potential. The goal is to translate “good growth” into measurable function and early mechanistic hypotheses you can test, prioritize, and refine.
To clarify how L. paracasei behaves in host-relevant systems, we assess barrier-associated readouts, immune signaling modulation profiles, and metabolism-linked markers in controlled in vitro or ex vivo setups—designed to generate interpretable evidence of interaction patterns rather than broad, non-specific claims.
We improve L. paracasei performance through adaptive evolution and/or metabolic engineering approaches aimed at practical outcomes—higher thermal/acid robustness, improved process survivability, or enhanced production of defined metabolites—so the strain is better aligned with real industrial constraints.
We develop and optimize high-density fermentation for L. paracasei by tuning media composition (carbon/nitrogen sources) and process parameters (pH, temperature, feed strategy). The deliverable is manufacturing-relevant biomass yield and activity retention—supported by structured process data.
Because L. paracasei can be sensitive to oxygen, heat, and dehydration stress, we design formulation strategies such as microencapsulation and freeze-drying with protective excipient systems to preserve viability and functional performance through processing, storage, and downstream application needs.
We run long-term, accelerated, and real-time stability programs to track L. paracasei viable counts across temperature and humidity conditions. Outputs include shelf-life trend data, critical degradation drivers, and quality-stability risk flags—useful for product development decisions and documentation.
