Bacteroides ovatus
Microbiome CRO Services

Creative Biolabs empowers microbiome R&D with integrated Bacteroides ovatus programs—covering selective isolation, genomic identification, mechanism-focused in vitro assays, anaerobic fermentation, and stability-minded formulation—so research teams can de-risk hypotheses, generate reproducible datasets, and progress from discovery questions to scalable evidence.

Proven by Leading Research Teams

End-to-end B. ovatus solutions built for reproducibility, speed, and transparent reporting that stands up to internal reviews and partner diligence.

Fig. 2. Akkermansia muciniphila microbiome CRO services partner-1 (Creative Biolabs Authorized)

Fig. 3. Akkermansia muciniphila microbiome CRO services partner-2 (Creative Biolabs Authorized)

Fig. 4. Akkermansia muciniphila microbiome CRO services partner-3 (Creative Biolabs Authorized)

Fig. 5. Akkermansia muciniphila microbiome CRO services partner-4 (Creative Biolabs Authorized)

Fig. 6. Akkermansia muciniphila microbiome CRO services partner-5 (Creative Biolabs Authorized)

Why B. ovatus Service Matters

B. ovatus is a prevalent human commensal with broad polysaccharide utilization. Its metabolism shapes short-chain fatty acid (SCFA) pools and interfaces with epithelial barrier status and immune tone—making it a high-value chassis for diet–microbe–host studies and next-generation commensal development.

Creative Biolabs offers a tightly linked platform—from strain discovery to functional readouts and viability-focused scale-up—so your B. ovatus work streams remain coherent, auditable, and aligned to hypothesis-driven endpoints such as SCFAs, barrier markers, cytokine panels, and quantitative tracking.

B. ovatus strains (Creative Biolabs Original)

Service Portfolio for B. ovatus Research

Microbial Isolation and Screening Services

We isolate and enrich B. ovatus from human/animal fecal or biospecimens under rigorously controlled anaerobiosis. Primary screens track colony morphology, growth kinetics, and preliminary fiber use. We establish master/working banks of B. ovatus with traceable metadata to expedite downstream characterization and reproducibility across multi-batch studies.

Microbial Identification Services

To verify B. ovatus at species and strain levels, we combine 16S rRNA, WGS, and MALDI-TOF. Deliverables include phylogenetic placement, PUL (polysaccharide utilization loci) highlights, and SNP-based strain fingerprints. These insights rank B. ovatus candidates for mechanistic assays, fermentation suitability, and formulation research.

Specific Primers and Probes Design

We design and validate qPCR/ddPCR primer–probe sets for B. ovatus using conserved loci or PUL targets. Assays include efficiency, linearity, LoD/LoQ, and matrix-tolerance checks to quantify B. ovatus in complex consortia and longitudinal models, enabling precise tracking alongside metabolite and barrier readouts.

Carbohydrate Fermentative Profiles

We profile B. ovatus utilization of inulin, resistant starch, arabinoxylans, and related fibers. Kinetics include OD/pH changes, SCFAs (acetate, propionate), and cross-feeding indicators. Results classify B. ovatus strains by substrate preference and fermentation performance to inform prebiotic selection and co-culture design.

Host-Microbe Interaction Tests

Using epithelial monolayers and gut organoids, we assess B. ovatus (cells, lysates, supernatants) on TEER, tight-junction proteins, and mucin expression. Configurable oxygen and mucus conditions differentiate barrier-supportive from disruptive signals, providing mechanism-relevant evidence for B. ovatus strain prioritization and formulation hypotheses.

In Vitro Tests of Immune System Modulation

We quantify B. ovatus effects in PBMC, macrophage, and dendritic-cell systems. Cytokine panels (e.g., IL-10, IL-22-linked pathways, TNF-α), PRR/TLR responses, and polarization markers distinguish signals from whole cells versus lysates/supernatants. Results guide substrate selection and define target readouts for scale-up.

Microbial Fermentation Services

We develop anaerobic fermentation for B. ovatus from shake flask to lab/pilot scale. DoE-guided media, pH/redox, and feeding strategies yield high-viability biomass or conditioned media with specified SCFA ranges. Batch records and in-run QC support reproducibility and future tech transfer.

Microbial Formulation Service

We address B. ovatus oxygen sensitivity through antioxidant systems, cryo/lyoprotectants, and microencapsulation/embedding approaches. Stress-challenge testing (temperature, humidity, oxygen) benchmarks viability and functional signatures, enabling data-driven selection of excipients for storage and transport windows.

Workflow: A Clear Path from Scope to Data

Program Scoping

Define hypotheses, matrices, success criteria, and B. ovatus endpoints (e.g., SCFAs, barrier markers, qPCR/ddPCR tracking).

Specimen Onboarding

Anaerobic intake, risk assessment, chain-of-custody, and initial culture planning for B. ovatus enrichment.

Isolation & Strain Banking

Selective isolation under strict redox control; master/working banks of B. ovatus with full metadata.

Molecular Confirmation & Assay Build

16S/WGS/MALDI-TOF ID, PUL notes, primer–probe design, and fit-for-purpose host-cell/immune assays.

Fermentation & Functional Testing

DoE-optimized runs; SCFAs, barrier, and cytokine readouts; in-run QC and interim reviews.

Reporting & Next Steps

Comprehensive report, raw data, SOPs, and optional formulation screens or scale-up planning.

Why Creative Biolabs for B. ovatus?

Anaerobe-First Infrastructure

Purpose-built isolators, gas-controlled bioreactors, and oxygen-trace analytics preserve B. ovatus phenotypes.

Mechanism-Anchored Assays

Barrier, immune, and metabolite readouts connect B. ovatus activity to decision-ready biological meaning.

Industrial-Grade Data Integrity

Traceable metadata, version-controlled SOPs, and audit-friendly reporting streamline downstream submissions.

Design-for-Scale Thinking

Process and stabilization insights that anticipate scale-up demands for B. ovatus projects.

Cross-Functional Team

Microbiologists, immunologists, and bioprocess engineers collaborate to shorten iteration cycles.

Transparent Collaboration

Frequent check-ins, real-time dashboards, and actionable recommendations at each stage.

Research Applications for B. ovatus

IBDs Treatment

Selected B. ovatus strains, evaluated in preclinical colitis settings, are associated with reduced inflammatory markers and improved epithelial metrics versus bulk fecal material, supporting strain-level, mechanism-oriented exploration under controlled conditions.

Diet–Barrier–Metabolism Axis

With glucomannan and related fibers, B. ovatus can generate indoleacetic acid signals that engage AhR pathways, correlate with barrier integrity, and modulate systemic endpoints in model systems designed for metabolic research questions.

Immune System Modulation

B. ovatus influences cytokine landscapes, including profiles linked to IL-22 and mucosal homeostasis. In vitro co-cultures help parse cell-type specificity and distinguish whole-cell versus metabolite-driven effects across assay conditions.

Gut–Brain Chemical Signatures

By shifting SCFAs (acetate, propionate) and GABA-adjacent metabolites, B. ovatus contributes to gut chemical networks. Quantitative assays track neurotransmitter-relevant changes alongside epithelial and immune readouts in controlled systems.

Pathogen Exclusion Models

As an abundant commensal, B. ovatus can support colonization resistance paradigms in vitro, enabling controlled tests of niche occupancy, substrate competition, and secreted-factor effects during community assembly experiments.

GvHD-Relevant Dysbiosis Studies

Research explores whether B. ovatus presence relates to lower-gut outcomes in dysbiosis-associated GvHD models. RUO assays examine composition, barrier, and cytokine patterns to inform hypothesis-driven consortia designs.

Fig. 8 Sample submission form (Creative Biolabs Original)

Partner with our specialists to drive your B. ovatus program from concept to results through a tailored, outcome-focused plan.

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B. ovatus Related Products

Explore Creative Biolabs' B. ovatus products below:

Product Name	Catalog No.	Target	Product Overview	Size	Price
*Bacteroides ovatus; 24398*	LBST-027FG	Bacteroides	An anaerobic, mesophilic bacterium. Thalli are rod-shaped, single or paired, Gram-negative.	200 µg	$1,560.00
*Bacteroides ovatus; 359491*	LBST-028FG	Bacteroides	An anaerobic, mesophilic bacterium. Thalli are rod-shaped, single or paired, Gram-negative.	200 µg	$1,605.00
*Bacteroides ovatus Genomic DNA*	LBGF-0925-GF224	Bacteroides DNA	High-quality, intact genomic DNA isolated from Bacteroides ovatus; purified and ready-to-use for PCR, qPCR, and Next-Generation Sequencing.	5 µg	$1,020.00

FAQs

We integrate MALDI-TOF, 16S rRNA, and whole-genome sequencing. Reports include phylogeny, PUL notes, and SNP fingerprints, ensuring strain-level clarity that supports substrate selection, assay design, and longitudinal tracking in complex matrices.

SCFAs (acetate, propionate), epithelial barrier metrics (TEER, tight-junction proteins), and immune signatures (e.g., IL-22-linked panels) together provide a multidimensional view, enabling confident comparisons across strains, substrates, and culture conditions.

Yes. We develop DoE-guided anaerobic fermentations to lab/pilot scale and evaluate cryo/lyoprotectants and encapsulation approaches, benchmarking viability and function after transport and storage stress to guide formulation selection.

Customized qPCR/ddPCR primer–probe sets target conserved loci or PUL signatures. Validations cover efficiency, LoD/LoQ, and matrix effects, enabling sensitive, reproducible quantification across time points and sample types.

Other Resources

Creative Biolabs' Live Biotherapeutics - Brochure

Probiotic Strain Products for NGP Research - Brochure

Custom Small-scale Probiotic Production - Brochure

Live Biotherapeutics - Creative Biolabs - Video

References

Ihekweazu, Faith D., et al. "Bacteroides ovatus promotes IL-22 production and reduces trinitrobenzene sulfonic acid–driven colonic inflammation." The American journal of pathology 191.4 (2021): 704. https://doi.org/10.1016/j.ajpath.2021.01.009
Nie, Qixing, et al. "Glucomannan promotes Bacteroides ovatus to improve intestinal barrier function and ameliorate insulin resistance." Imeta 3.1 (2024): e163. https://doi.org/10.1002/imt2.163
Lechuga, Susana, et al. "Understanding disruption of the gut barrier during inflammation: Should we abandon traditional epithelial cell lines and switch to intestinal organoids?." Frontiers in Immunology 14 (2023): 1108289. https://doi.org/10.3389/fimmu.2023.1108289

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Bacteroides ovatus Microbiome CRO Services