B. xylanisolvens requires rigorous anaerobic handling to preserve viability and phenotype. Creative Biolabs isolates the strain under strictly controlled environments and applies high-throughput screening platforms to identify B. xylanisolvens variants with strong xylanase activity and robust growth performance, establishing a reliable seed bank for downstream development.
To quantify the fiber-metabolizing potential of B. xylanisolvens, we analyze its utilization of xylan, arabinoxylan, and related fibers. Through targeted metabolite profiling, we measure short-chain fatty acids—particularly butyrate and propionate—providing clear insight into how B. xylanisolvens transforms dietary substrates and contributes to gut environmental modulation.
Creative Biolabs integrates in vitro cellular models and animal-based systems to map how B. xylanisolvens degrades complex polysaccharides and influences microbial ecosystem structure. We assess effects on gut barrier indicators, metabolic pathways, mucus integrity, and microbiome-derived signaling, helping clients link molecular actions with functional outcomes.
Our immunology platform evaluates how B. xylanisolvens and its surface-associated polysaccharides influence cytokine production and immune cell phenotypes. Using macrophage and dendritic cell models, we quantify IL-10 induction, Th1/Th2-related markers, and broader immunomodulatory signatures to support immune-related research hypotheses.
Creative Biolabs performs comprehensive safety assessment, including whole-genome sequencing to identify antimicrobial resistance or virulence markers, phenotypic antibiotic susceptibility profiles, hemolytic activity evaluation, and metabolite toxicity screening. These datasets ensure researchers can advance B. xylanisolvens programs aligned with global safety expectations.
Scaling B. xylanisolvens requires mastery of strict anaerobic bioprocessing. We design tailored fermentation strategies that optimize carbon sources, nitrogen inputs, redox status, and pH control. These methods enable high-density biomass production suitable for formulation development, functional testing, and pilot-scale research activities.
Given B. xylanisolvens’s high sensitivity to oxygen and gastric conditions, Creative Biolabs develops microencapsulation, cryoprotectant-enhanced freeze-drying, and targeted-release coating technologies. These solutions improve strain survival during processing, storage, and gastrointestinal transit while supporting colonization in relevant gut regions.
We perform accelerated and real-time stability studies for B. xylanisolvens formulations under varied conditions of temperature, humidity, and packaging. By tracking CFU decline and metabolic activity shifts, we establish science-based shelf-life and recommend optimal packaging formats to maintain product performance.
