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Bacteria belonging to R. albus contain cellulosomes that allow them to adhere to and digest cellulose, and their genomes encode cellulase and hemicellulase. R. albus is a primary cellulose degrader that produces acetate usable by its bovine host. R. albus, an anaerobic ruminal bacterium, produces acetate, ethanol, formate, hydrogen, and carbon dioxide from carbohydrates. Hydrogen-producing R. albus is more abundant in healthy individuals than in patients with Crohn’s disease and shows probiotic effects. No R. albus was found in the faeces of children with autism, while high levels of R. albus were found in the faeces of control children.
Gut microbiota plays an important role in gut-brain communication and has been linked to neuronal disorders. The researchers investigated the neuroprotective effects of R. albus with probiotic potential on oxidative stress SH-SY5Y neuroblastoma cells and animals. Treatment with heat-killed R. albus reduced the level of ROS, and the levels of SOD and GSH increased in oxidatively stressed brains. Heat-killed R. albus can inhibit oxidative stress-mediated neuronal cell damage and produce the neuroprotective effect. Therefore, R. albus could be a source of potential therapeutic approaches to alleviate oxidative stress-induced brain damage.
Fig.1 Histological analysis of brain, liver, and kidneys of rats oxidatively stressed with sodium arsenate (As). (Park, 2017)
We supply a variety ofR. albus strains of different preservation numbers. If you need other strains, please contact us.
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For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.