Creative Biolabs establishes robust, strictly anaerobic pipelines to isolate and screen R. albus from rumen, fecal, or synthetic consortia samples. Strains are evaluated for growth, morphology, carbohydrate utilization, and cellulolytic performance, enabling selection of high-value R. albus candidates for downstream applications and mechanistic studies.
Our microbiologists deploy 16S rRNA sequencing, whole-genome sequencing, and targeted qPCR/dPCR panels to accurately identify R. albus in complex microbiome backgrounds. This service confirms strain identity, detects co-colonizing relatives, and supports clear strain tracking in in vitro systems or animal models focused on R. albus.
Leveraging high-content anaerobic fermentation platforms, Creative Biolabs systematically characterizes R. albus carbohydrate fermentative profiles on cellulose, hemicellulose, arabinoxylans, and defined prebiotics. We quantify sugar utilization, short-chain fatty acid output, and gas production, revealing how R. albus deconstructs plant polysaccharides and contributes to butyrate and other metabolites.
Functional screening programs interrogate R. albus enzyme repertoires, signaling potential, and ecosystem roles. Using enzyme assays, omics readouts, and co-culture models, Creative Biolabs maps pathways such as cellulase/xylanase activities, feruloyl esterase functions, and oxidative stress modulation to build mechanism-of-action hypotheses around R. albus behavior.
To understand how R. albus influences host biology, Creative Biolabs develops customized host–microbe interaction assays using intestinal epithelial cells, immune cells, and organoid or gut-on-chip systems. These models capture barrier integrity, cytokine profiles, and oxidative stress parameters in response to live or heat-killed R. albus or its secretome.
Our anaerobic fermentation group designs and scales R. albus fermentation processes from milliliter screening to liter-scale development. We optimize medium composition, pH, redox potential, and gas composition to maximize biomass, enzyme expression, or specific metabolites, providing ready-to-use cell banks, supernatants, or lysates of R. albus for further research.
Creative Biolabs systematically evaluates R. albus stress responses under variations in pH, bile salts, oxygen exposure, temperature, and osmotic pressure. We track viability, transcriptional changes, and functional outputs, enabling rational strategy design for stabilization, formulation, and process robustness of R. albus in vitro and in vivo models.
Using synthetic biology and classical strain improvement, Creative Biolabs offers R. albus probiotics engineering and optimization services. Projects may include enhancing cellulose-degrading capacity, improving oxygen tolerance, tailoring metabolite profiles, or improving encapsulation compatibility, always within research frameworks that respect biosafety and regulatory expectations for R. albus.
