Nucleic Acid References

Molecular diagnostics is one of the fastest growing fields in laboratory medicine. Nucleic Acid Reference Materials are crucial in molecular diagnostics and research. They serve as certified positive samples for quality control, ensuring the accuracy and reliability of nucleic acid identification and quantification. These materials are used to calibrate instruments, validate diagnostic methods, and provide a benchmark for experimental results. In order to improve the accuracy of nucleic acid determination, a variety of nucleic acid standard materials have been developed. Reference materials can provide a frame of reference for quality control of qualitative and quantitative detection processes for nucleic acid.

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Fig.1 Nucleic acid reference materials from probiotics. (Creative Biolabs Authorized)

Inactivated Probiotics

Probiotic nucleic acid reference materials.

Featured Subcategories

  • Heat-inactivated intestinal bacteria
  • Heat-inactivated next-generation probiotics
  • Heat-inactivated food probiotics

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Inactivated Microorganisms

Non-probiotic and pathogenic microbial nucleic acid reference materials.

Featured Subcategories

  • Heat-inactivated pathogen
  • Heat-inactivated fungi
  • Heat-inactivated phages

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Fig.2 Nucleic acid reference materials from non-probiotics. (Creative Biolabs Authorized)

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Frequently Asked Questions

What are the applications of Nucleic Acid Reference Materials?

Nucleic Acid Reference Materials (NARMs) have a wide range of applications in various fields:

  • Quality Control and Calibration: They are used to ensure the accuracy and reliability of nucleic acid detection and quantification methods. This is crucial in laboratories to maintain high standards in diagnostic testing.
  • Diagnostic Testing: NARMs are essential in diagnosing infectious diseases, genetic disorders, and other conditions through techniques like PCR and digital PCR.
  • Research and Development: They provide a benchmark for experimental results, helping researchers validate new techniques and compare results across different studies.
  • Regulatory Compliance: NARMs help laboratories comply with regulatory standards and guidelines, ensuring that their testing methods meet required specifications.
  • Educational Purposes: They are used in academic settings to teach students about nucleic acid analysis techniques and quality assurance practices.

What are the commonly used Nucleic Acid Reference Materials?

Commonly used Nucleic Acid Reference Materials include:

  • Human Genomic DNA: Used for various genetic testing and research applications.
  • Pathogen DNA/RNA: Essential for diagnosing infectious diseases through techniques like PCR.
  • Cancer Genomics: Specific reference materials for detecting mutations associated with different cancers.
  • Inherited Disorders: Materials for diagnosing genetic disorders.
  • Quality Control Reagents: Used for long-term monitoring of diagnostic testing performance.

Which customers will use nucleic acid reference materials?

Customers who use Nucleic Acid Reference Materials (NARMs) span a variety of fields:

  • Diagnostic Laboratories: To validate and calibrate their diagnostic tests for diseases and genetic conditions.
  • Pharmaceutical Companies: Rely on NARMs for research and development of new drugs and therapies.
  • Academic and Research Institutions: For teaching and conducting scientific research.
  • Biotechnology Firms: For the development and quality control of biotechnological products and assays.
  • Food and Beverage Industry: To ensure the quality and safety of their products, especially those involving probiotics.
  • Environmental Monitoring Agencies: To detect and study environmental pollutants and pathogens.
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