Microbiome Biospecimens

Welcome to the specialized biospecimens division of Creative Biolabs.

The rapidly expanding field of microbiome research holds the key to developing the next generation of diagnostics and live biotherapeutic products (LBPs). However, the integrity and standardization of the starting material - the biological specimen - is paramount. The complex microbial communities found in samples like feces, saliva, and breast milk are highly sensitive to collection, processing, and storage conditions. Reproducible and reliable research hinges on samples that truly reflect the in vivo microbial state.

Overview: Specialized Samples for Complex Microbial Environments

Biospecimens are biological materials collected from human donors and ethically preserved for research use. At Creative Biolabs, our biorepository focuses on samples rich in microbial communities and immune components, providing a unique resource for translational research. Key Applications Supported:

• Developing novel microbial diagnostics.
• Identifying disease-associated microbial signatures (biomarkers).
• Screening and validating live biotherapeutic product (LBP) candidates.
• Studying vertical transmission of the microbiome (mother-infant health).

Our Product Catalog: Browse Samples by Type

Click on the category below to view the specific product formats, available cohorts, and processing details for your research focus.

Click on a product category name (e.g., Fecal Samples) to go directly to the detailed product listing page.

Key Advantages of Our Samples

• Optimized Preservation Protocols
  Microbial biospecimens require specialized handling. Our SOPs are engineered to maintain the viability and structure of complex microbial communities:
  • Minimizing TID (Time to Deep Freeze): Our collection methods ensure the shortest possible time between collection and stabilization/freezing, minimizing ex vivo community shifts.
  • Standardized Buffer Use: We employ DNA/RNA stabilization buffers that chemically lock the microbial profile at the moment of collection, ensuring fidelity for downstream sequencing.
  • High Purity Nucleic Acids: Our isolation kits are validated to maximize yield and purity of microbial DNA/RNA from challenging matrices, crucial for 16S rRNA gene sequencing and whole-genome shotgun sequencing.
• Support for Live Biotherapeutic Product (LBP) Research

For companies developing live cultures, we offer unique access to high-quality, viable fecal material collected and stored under conditions that maximize microbial viability, supporting culturomics and donor screening initiatives

Applications in Microbiome Research and Beyond

Our biospecimens are the critical starting point for cutting-edge research across diverse scientific disciplines:

• Next-Generation Sequencing (NGS) Studies: Utilizing isolated DNA/RNA for 16S rRNA gene sequencing, whole-genome shotgun (WGS) sequencing, and metatranscriptomics to profile microbial community structure and function.
• Metabolomics and Lipidomics: Analyzing biofluids (plasma, urine, fecal filtrate) paired with microbial data to understand how the microbiome influences host metabolism and disease progression.
• Immunology and Inflammation: Using paired blood derivatives (PBMCs) and gut samples to assess the systemic immune response triggered by specific microbial compositions (e.g., in autoimmune diseases).
• Nutritional Science: Investigating the impact of probiotics, prebiotics, and specific dietary interventions on gut health and systemic markers using fecal and blood samples from intervention cohorts.

Partner with Creative Biolabs Today

The future of microbiome science depends on the reliability of its raw material. By choosing us, you are selecting a partner dedicated to the rigorous standards required for microbial biospecimen integrity. Stop spending valuable time and budget re-running experiments due to poor sample quality.

Ready to power your research with the gold standard in microbiome samples?

Frequently Asked Questions (FAQs)