Pediococcus pentosaceus as Next Generation Probiotics

Creative Biolabs has established a cutting-edging platform by assembling top-class scientific experts and integrating state-of-the-art technologies as well as substantial expertise in the development of Pediococcus pentosaceus as next-generation probiotics (NGPs). Our experienced scientists are glad to apply this special expertise to help our worldwide customers with their meaningful research projects.

Introduction of P. pentosaceus

Belonging to Gram-positive, anaerobic Firmicutes, P. pentosaceus is coccus-like microbe, non-motile, non-spore forming. P. pentosaceus are categorized as a "lactic acid bacteria" because the end product of its metabolism is lactic acid. P. pentosaceus can be cultured at 35 ℃-40 ℃ but are unable to grow at 50 ℃. P. pentosaceus can grow in pH 4.5-8.0 and is more stably at the more acidic pH range. Pediococcus are unique in that they form tetrads, which are formed via cell division in two perpendicular directions in a single plane. They can be found in plant materials, ripened cheese, and a variety of processed meats. P. pentosaceus is industrially important due to its ability as a starter culture to ferment foods.

Applications of P. pentosaceus in the Field of Biotechnology

P. pentosaceus is being studied for its ability to produce an antimicrobial agent as well as its use in food preservation. P. pentosaceus can produce an antimicrobial agent known as bacteriocins against several species of Lactobacillus, lactococcus, leuconostoc, pediococcus, staphylococcus, enterococcus, bacillus and listeria. Antimicrobial agents are produced by bacteria to limit the growth of competitors and/or other harmful bacteria. One P. pentosaceus strain, LAB6 exhibited a cholesterol-lowering effect in various degrees, 19-59% in the absence and 14-9% in the presence of bile salts. Moreover, previous reports have shown that P. pentosaceus is also involved in catheter-associated with infection and endocartitis. Further clinical trials are necessary to conclusively prove the benefits of P. pentosaceu.

Develoment of P. pentosaceu as NGPs at Creative Biolabs

Most of the current research is associated with the applications of P. pentosaceus in the field of biotechnology. Continuing research is still being done to refine P. pentosaceus as a starter culture for fermentation. Valuable lessons have been learned from working with traditional probiotics, Creative Biolabs is committed to exploring the kinds of organisms likely to be used as novel microbial therapeutics and P. pentosaceu is a good candidate. Our multidisciplinary teams work together closely to address these scientific and technical challenges.

Highlights of Our P. pentosaceu Drug Discovery Services

  • Top-rated customer experience
  • High flexibility and cost-effectiveness
  • Reliability and information security
  • Tailored research & services

Our comprehensive powerful platform, professional technical scientists and abundant experience make Creative Biolabs a perfect partner to help our clients in the development of Pedioccus pentosaceus as NGPs. Just feel free to contact us and communicate with us about your specific puzzles. Our PhD scientists will offer you professional solutions as soon as possible.

Reference

  1. Bajpai, V.K.; et al. Characterization and antibacterial potential of lactic acid bacterium Pediococcus pentosaceus 4I1 isolated from freshwater fish Zacco koreanus. Frontiers in microbiology. 2016, 7: 2037.
CAT Product Name Product Overview
LBP-001FG Prevotella copri Powder Freeze-dried Prevotella copri (P. copri) Powder.
LBST-001FG Prevotella copri; 13464 Prevotella copri was isolated from human feces. Its cells are Gram-negative rods that are anaerobic and nonspore-forming.
LBST-002FG Prevotella copri; 58058T Prevotella copri was isolated from 52-year-old healthy man. Its cells are Gram-negative rods that are anaerobic and nonspore-forming.
LBST-003FG Prevotella copri Hayashi et al. 2007 emend. Hahnke et al. 2016 Prevotella copri was isolated from pig feces. Its cells are Gram-negative rods that are anaerobic and nonspore-forming.
LBST-004FG Prevotella copri; CB7 Prevotella copri was isolated from human feces. Its cells are Gram-negative rods that are anaerobic and nonspore-forming.
LBST-005FG Prevotella sp. Prevotella sp. was isolated from human feces. Its cells are Gram-negative rods that are anaerobic and nonspore-forming.
LBST-006FG Prevotella hominis Liou et al. Prevotella hominis cells are Gram-negative, non-spore-forming, nonmotile rods and strictly anaerobic. Colonies are approximately 0.5–1mm in diameter, slightly translucent, circular, entire, slightly convex and smooth after 2 days at 37 °C on modified GAM agar plates under anaerobic conditions.
LBST-007FG Prevotella stercorea Prevotella stercorea is an anaerobe, mesophilic, Gram-negative bacterium that was isolated from human faeces.
LBST-008FG Prevotella intermedia Prevotella intermedia is a Gram-negative, obligate anaerobic pathogenic bacterium involved in periodontal infections, including gingivitis and periodontitis, and often found in acute necrotizing ulcerative gingivitis. Prevotella intermedia use steroid hormones as growth factors, so their numbers are higher in pregnant women.
LBST-009FG Prevotella histicola Downes et al. 2008 Prevotella histicola is Gram-negative bacillus that are obligately anaerobic, vary in pigmentation and are non-motile.

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