Prevotella copri was isolated from human feces. Its cells are Gram-negative rods that are anaerobic and nonspore-forming.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information
Product Overview
Prevotella copri was isolated from human feces. Its cells are Gram-negative rods that are anaerobic and nonspore-forming.
Target
Prevotella
Genus
Prevotella
Strain Designation
H. Hayashi CB7
Application
Study and research
Culture Medium
Blood agar
Culture Conditions
37°C; Anaerobic
Source
Human feces
Risk Group
2
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
Prevotella is a genus of anaerobic Gram-negative bacteria of the Bacteroidetes phylum, which also includes the clinically important genera Bacteroides and Porphyromonas. Prevotella strains are classically considered commensal bacteria due to their extensive presence in the healthy human body and their rare involvement in infections. Prevotella spp. are members of the oral, vaginal, and gut microbiota and are often recovered from anaerobic infections of the respiratory tract. Prevotella spp. predominate in periodontal disease and periodontal abscesses. Regarding Prevotella, studies focused on the associations between the diverse species, genome and habitats with dietary patterns, health and disease. Evidence revealed beneficial effects of some Prevotella strains in the gut such as improving CVD risk factor profile and glucose metabolism. Most studies reported that vegetarians harbour higher numbers of Prevotella species as well as a high Prevotella/Bacteroides ratio compared with non-vegetarians; omnivores. Nevertheless, there is a need for more studies in humans to ascertain a causal and potential disease-triggering role for Prevotella and more in-depth metagenomic studies are needed in order to reveal the health- or disease-modulating properties.
Alternative Names
Prevotella copri
FAQs Customer Reviews Related Products
What is the optimal growth condition for Prevotella copri?
Prevotella copri thrives under anaerobic conditions with temperatures around 37°C. Cultivation should be done using enriched media suitable for anaerobic bacteria, ensuring the environment remains oxygen-free to maintain the viability and activity of the bacteria. This strain is particularly sensitive to oxygen and requires strict anaerobic techniques during handling and cultivation.
How is the genomic DNA of Prevotella copri extracted for research purposes?
Genomic DNA extraction from Prevotella copri involves using an anaerobic chamber to maintain the cells' integrity during lysis. Typically, a mechanical disruption followed by a phenol-chloroform extraction method is employed to ensure high-quality DNA suitable for downstream applications such as PCR and sequencing.
What are the key applications of Prevotella copri in gut microbiome research?
Prevotella copri is widely used in studies investigating the gut microbiome's role in metabolic health, including its effects on glucose homeostasis and insulin resistance. It is also utilized in exploring the interactions between diet and gut microbiota, providing insights into its potential as a biomarker for dietary habits and related health outcomes.
How is Prevotella copri prepared for use in in vivo studies?
For in vivo studies, Prevotella copri is typically prepared by growing the bacteria to the desired density, followed by centrifugation to collect the cells. These cells are then resuspended in a suitable buffer or medium. Proper anaerobic techniques must be employed throughout the preparation process to maintain cell viability.
How can the metabolic activity of Prevotella copri be assessed in vitro?
The metabolic activity of Prevotella copri can be evaluated using various assays, such as measuring the production of short-chain fatty acids (SCFAs) through gas chromatography or assessing carbohydrate fermentation profiles. These methods provide insights into the bacterium's metabolic capabilities and its potential impacts on the host gut environment.
High-Quality Strain for Advanced Research
Creative Biolabs' Prevotella copri is a superior strain for advanced gut microbiome studies, providing high-quality genomic material that supports detailed and reliable research outcomes in various applications.
Excellent for Host-Microbe Interaction Studies Prevotella copri demonstrates significant advantages in host-microbe interaction experiments, offering high specificity and sensitivity. Its reliability makes it an invaluable tool for detailed gut microbiota research.
Reliable and Robust Performance
In immune modulation studies, Prevotella copri from Creative Biolabs delivers consistent results. Its robust performance and stability under anaerobic conditions set it apart from other suppliers' strains.
Simplified Handling and Preparation
The handling and preparation of Prevotella copri are straightforward, thanks to Creative Biolabs' detailed guidelines. This facilitates smooth incorporation into various research protocols, enhancing workflow efficiency.
High Viability Post-Thaw Prevotella copri maintains excellent viability post-thaw, making it ideal for repeated experimental use. This quality from Creative Biolabs ensures dependable results across multiple research applications.
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