Prevotella is a genus of anaerobic Gram-negative bacteria of the Bacteroidetes phylum, which also includes the clinically important genera Bacteroides and Porphyromonas. Prevotella strains are classically considered commensal bacteria due to their extensive presence in the healthy human body and their rare involvement in infections. Prevotella spp. are members of the oral, vaginal, and gut microbiota and are often recovered from anaerobic infections of the respiratory tract. Prevotella spp. predominate in periodontal disease and periodontal abscesses. Regarding Prevotella, studies focused on the associations between the diverse species, genome and habitats with dietary patterns, health and disease. Evidence revealed beneficial effects of some Prevotella strains in the gut such as improving CVD risk factor profile and glucose metabolism. Most studies reported that vegetarians harbour higher numbers of Prevotella species as well as a high Prevotella/Bacteroides ratio compared with non-vegetarians; omnivores. Nevertheless, there is a need for more studies in humans to ascertain a causal and potential disease-triggering role for Prevotella and more in-depth metagenomic studies are needed in order to reveal the health- or disease-modulating properties.
Alternative Names
Prevotella copri
FAQs Customer Reviews Related Products
How should Prevotella copri be stored before use in experiments?
Prevotella copri should be stored at -80°C in cryoprotectant solutions such as 15% glycerol to maintain viability. Prior to use, thaw the culture rapidly and immediately transfer it to anaerobic media to ensure optimal recovery and growth.
What are the recommended steps for preparing Prevotella copri cultures for experimental assays?
Thaw frozen stocks rapidly and inoculate them into pre-reduced anaerobic media. Incubate the cultures at 37°C in an anaerobic chamber for 24-48 hours until reaching the desired density. Subculture if necessary to ensure a healthy, active culture for experiments.
How can Prevotella copri be quantified in a mixed microbial community?
Quantification in mixed microbial communities can be performed using real-time PCR with species-specific primers. This technique provides precise quantification of Prevotella copri within complex microbiota samples, allowing for detailed population analysis.
What techniques are used to study the interaction of Prevotella copri with host cells?
Techniques such as co-culture assays with epithelial cells, gut barrier integrity assays using transepithelial electrical resistance (TEER), and cytokine profiling can be used to study interactions. These methods help in understanding the impact of Prevotella copri on host cellular functions and immune responses.
Outstanding Quality for Microbiota Research
The quality of Creative Biolabs' Prevotella copri Hayashi et al. 2007 emend. Hahnke et al. 2016 is exceptional. It has significantly advanced our research on gut microbiota, providing reliable and consistent results.
Superior Strain for Metabolic Studies
Creative Biolabs' Prevotella copri strain is indispensable for metabolic research. Its ability to influence gut microbiota and metabolic pathways makes it ideal for studying conditions like obesity and diabetes.
Excellent for Inflammatory Disease Research
Using Prevotella copri from Creative Biolabs has been pivotal in our studies on inflammatory diseases. Its role in modulating immune responses is crucial for understanding conditions like rheumatoid arthritis.
Superior Support for Microbial Research
Creative Biolabs provides an outstanding Prevotella copri strain that has enhanced our research on microbial colonization and host interactions. It is an excellent choice for advanced microbiome studies.
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