Enterococcus hirae Microbiome CRO Services

Enterococcus hirae is gaining attention as a mechanistically informative enterococcal species across immunology, microbiome, and bioprocess research. Creative Biolabs supports biopharma, academia, and product developers with study-ready E. hirae workflows that turn isolates, phenotypes, and functional readouts into decision-grade datasets for strain selection, comparability, and downstream development.

Trusted by R&D Teams Worldwide

Trusted by global R&D teams seeking reproducible E. hirae data under real project timelines.

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Why E. hirae Focused CRO Studies Matter

E. hirae has long served as a model organism for membrane bioenergetics, ion transport, and copper homeostasis, providing a rich base for hypothesis-driven microbiology. In practical terms, E. hirae projects often hinge on three questions: what the strain truly is (identity and stability), how it behaves under project constraints (media, oxygen, pH, bile salts, temperature, co-culture), and where the safety/resistance boundaries sit for the intended research scenario (containment, markers, and project-specific hygiene constraints).

That is why an E. hirae plan usually benefits from a staged design: start with clean isolation or material verification, lock strain IDs early, then expand into stress and functional profiling only after comparability criteria are met. This sequencing reduces late-stage surprises such as misassigned taxonomy, phenotype drift after passaging, or activity that appears only under a single lab condition.

E. hirae microbiome services (Creative Biolabs Original)

E. hirae Microbiome CRO Service Modules

Microbial Isolation and Screening Services

We isolate E. hirae from complex samples using selective workflows, then screen multiple colonies to map diversity within the E. hirae population. Early screening can include growth kinetics, stress tolerance, and metabolic fingerprints so only the most project-relevant E. hirae candidates advance to deeper characterization.

Microbial Identification Services

Accurate naming drives accurate science. Our identification workflow confirms E. hirae using tiered methods (phenotypic and molecular), resolving close enterococcal neighbors and mixed cultures. For E. hirae candidates, we also support strain tracking across passages to minimize identity drift and ensure comparability across study stages.

Biological Safety Test Services

E. hirae research requires safety-aware datasets that match your use scenario. We assess key biosafety attributes for E. hirae isolates, including contaminant checks and risk-relevant profiling, then deliver documentation that supports internal review, study reproducibility, and cross-site transfer of materials under appropriate controls.

Antimicrobial Susceptibility Testing

E. hirae programs often need defensible susceptibility profiles to guide containment, selection, and downstream study planning. We generate standardized MIC/MBC-style panels for E. hirae under defined conditions, with options to align test agents to your workflow, selection markers, or process hygiene needs.

Functional and MoA Screening

To move beyond “present or absent,” we map what E. hirae does in context. Functional and MoA screening for E. hirae can include metabolite-linked activity, stress-triggered phenotype switching, and pathway-relevant assays designed to connect a mechanistic hypothesis to measurable, repeatable outputs.

In Vitro Tests of Immune System Modulation

Immune-facing assays help clarify how E. hirae interfaces with innate and adaptive signaling in vitro. We evaluate E. hirae in defined cell-based systems (e.g., cytokine and activation-marker panels) with controlled bacterial inputs, enabling comparative ranking across E. hirae strains and culture states.

Host-Microbe Interaction Tests

Host interaction readouts can change drastically with culture state. We test E. hirae in co-culture or barrier-relevant models to quantify adhesion-related behavior, epithelial response signatures, and condition-dependent effects. These assays help distinguish E. hirae features that are intrinsic from those driven by media or stress.

Microbial Fermentation Services

When projects scale from plates to process, E. hirae behavior must be revalidated. Our microbial fermentation services support E. hirae growth optimization, controlled harvest, and batch-to-batch comparability, with in-process monitoring and post-run QC so your E. hirae material remains fit for research workflows.

Streamlined E. hirae Projects Workflow

1

Study Intake

Define E. hirae strain source, matrices, endpoints, timelines, stakeholders, and acceptance criteria in one plan.

2

Controlled Handling

Standardize E. hirae revival, passaging limits, storage, transport, and log sheets to reduce phenotypic drift.

3

Identity Confirmation

Verify E. hirae purity and taxonomy, then lock strain IDs for fully traceable long-term tracking.

4

Core Characterization

Run E. hirae growth, stress, and susceptibility panels under strict project-relevant boundary conditions and controls.

5

Functional Testing

Execute E. hirae MoA and host-interaction assays aligned tightly to your primary mechanistic working hypothesis.

6

Data Package Delivery

Deliver E. hirae reports, raw tables, QC records, and clear next-step recommendations for sponsor teams.

Service Advantages for E. hirae Projects

Study-Ready Rigor

Standardized execution keeps E. hirae datasets comparable across sites, analysts, timepoints, and validated instrument configurations.

Flexible Scope

E. hirae testing scales from rapid screens to multi-layer characterization without rework or protocol drift.

Mechanism-First Readouts

Assays prioritize biologically interpretable E. hirae functions, not generic microbe-only endpoints or overfit surrogate readouts.

Documentation Depth

Traceable records support E. hirae material handoffs, audits, internal governance reviews, and sponsor reporting needs.

Matrix Awareness

E. hirae protocols adapt to your sample type, exposure limits, co-culture complexity, and readout sensitivity.

Iteration Speed

Review loops refine E. hirae hypotheses quickly, reducing rework, wasted cycles, and avoidable assay failures.

E. hirae Applications across Research and Development

Immunology and oncology-adjacent research

Preclinical studies connect E. hirae exposure to measurable shifts in antigen-specific immune context and intratumoral CD8/Treg ratios, motivating mechanistic assays that track trafficking, cytokine signatures, and response durability rather than relying on taxonomy alone.

Veterinary and agricultural microbiome programs

Piglet-derived E. hirae strains have been evaluated in ETEC-associated diarrhea models with growth-related outcomes, while aquaculture work reports improved performance and challenge-model resilience under defined diets, supporting early strain screening for specific, species-tailored research goals.

Industrial QC and assay development

E. hirae supports disinfectant susceptibility and microbiological assay work, enabling SOP benchmarking, tolerance profiling, and method validation. It fits studies where assay organisms must respond predictably to agents or nutrients under incubation and readout rules.

Environmental and sanitary investigations

E. hirae appears in animal- and water-associated datasets used for contamination tracking, and its copper-handling biology supports experiments on transport and stress adaptation in polluted matrices, including EPS-mediated binding studies for metals under defined chemistry.

Sample submission form (Creative Biolabs Original)

Submit your sample request form to obtain an E. hirae research plan precisely aligned with your study objectives.

E. hirae Related Products

The following products are available to support standardized E. hirae research.

Product Name Catalog No. Target Product Overview Size Price
Enterococcus hirae LBST-108FG Enterococcus Enterococcus hirae is a Gram-positive coccus that was isolated from the rabbit manure. 200 µg $1,156.00
Enterococcus hirae; RS9 LBST-109FG Enterococcus Enterococcus hirae is a Gram-positive coccus that was isolated from the rabbit intestinal. 200 µg $1,156.00
Enterococcus hirae; 2-3 LBST-110FG Enterococcus Enterococcus hirae is a Gram-positive coccus that was isolated from about 5-10 days old young duck fecal stool. Inquiry
Enterococcus hirae; 336072 LBST-111FG Enterococcus Enterococcus hirae is a Gram-positive coccus. Inquiry
Enterococcus hirae Genomic DNA LBGF-0925-GF451 Enterococcus DNA This product contains high-quality, intact genomic DNA isolated from Enterococcus hirae Genomic DNA. It is a purified and ready-to-use DNA sample, ideal for a wide range of molecular biology applications, including PCR, qPCR, and Next-Generation Sequencing. 5 µg $1,120.00

FAQs

Yes. We lock an E. hirae reference bank, limit passages, and re-check identity plus sentinel phenotypes at predefined checkpoints. This flags batch effects early, preserves comparability across runs, and keeps functional readouts interpretable for sponsors.

Media composition, oxygen exposure, pH, and bile/salt stress can shift E. hirae growth and surface features. Align conditions to your use context, document them, and run stress boundaries with controls to improve reproducibility consistently.

We design E. hirae panels around your antibiotics, selection markers, or hygiene constraints. Results include methods, controls, and interpretive notes, so they support containment decisions, comparability reviews, and downstream planning with thresholds and traceable context.

References

  1. Miyauchi, E., et al. "Cell wall fraction of Enterococcus hirae ameliorates TNF‐α‐induced barrier impairment in the human epithelial tight junction." Letters in applied microbiology 46.4 (2008): 469-476. https://doi.org/10.1111/j.1472-765X.2008.02332.x
  2. Suchomel, Miranda, et al. "Enterococcus hirae, Enterococcus faecium and Enterococcus faecalis show different sensitivities to typical biocidal agents used for disinfection." Journal of Hospital Infection 103.4 (2019): 435-440. https://doi.org/10.1016/j.jhin.2019.08.014
  3. Kavitake, Digambar, et al. "Production, purification, and functional characterization of glucan exopolysaccharide produced by Enterococcus hirae strain OL616073 of fermented food origin." International Journal of Biological Macromolecules 259 (2024): 129105. https://doi.org/10.1016/j.ijbiomac.2023.129105
  4. Rong, Yihui, et al. "Reactivity toward Bifidobacterium longum and Enterococcus hirae demonstrate robust CD8+ T cell response and better prognosis in HBV-related hepatocellular carcinoma." Experimental cell research 358.2 (2017): 352-359. https://doi.org/10.1016/j.yexcr.2017.07.009
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