Freeze-dried Lactobacillus plantarum Powder
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information | |
---|---|
Product Overview | Freeze-dried Lactobacillus plantarum Powder |
Target | Lactobacillus |
Source | Human |
CFU Value | 5×10^11 |
Genetic Modifications | None |
Application | Used as live bacteria probiotic |
Appearance | White to light yellow powder |
Size | 1 kg |
Storage | Store at -20°C to -80°C. |
Shelf Life | 24 months |
Note | 1. Characters of the strain are genetically identified. 2. Types of probiotic blends/premixes could be provided based on the clients' requirements. 3. Tyndalized (Heat-Sterilized) specifications could be provided based on clients' requirements. 4. Complete data sheet is available based on the clients' requirements. 5. For research use only. Not intended for food, diagnostics, therapeutic or any in vivo human use. |
Target Introduction | |
---|---|
Introduction | Lactiplantibacillus plantarum is a widespread member of the genus Lactiplantibacillus and commonly found in many fermented food products as well as anaerobic plant matter. L. plantarum was first isolated from saliva, based on its ability to temporarily persist in plants, the insect intestine, and in the intestinal tract of vertebrate animals, it was designated as a nomadic organism. L. plantarum is a Gram-positive, bacilli-shaped bacterium. L. plantarum cells are rods with rounded ends, straight, generally, 0.9-1.2 μm wide and 3-8 μm long, occurring singly, in pairs, or in short chains. L. plantarum has one of the largest genomes known among the lactic acid bacteria and is a very flexible and versatile species. |
Alternative Names | Lactobacillus plantarum; L. plantarum |
Lactobacillus plantarum powder is primarily used in scientific research to explore its probiotic effects, including the enhancement of gut health, modulation of the immune system, and potential anti-inflammatory properties. Researchers also study its application in food preservation and fermentation processes.
Distinguishing characteristics of Lactobacillus plantarum powder include its high survivability in acidic and bile environments, its strong adhesion to intestinal epithelial cells, and its ability to produce antimicrobial peptides. These features make it an effective probiotic for various health applications.
Lactobacillus plantarum powder modulates the immune system by interacting with gut-associated lymphoid tissue (GALT), promoting the production of regulatory T cells, and enhancing the secretion of anti-inflammatory cytokines. These actions help maintain immune balance and protect against infections.
Lactobacillus plantarum powder is produced through controlled fermentation processes, followed by freeze-drying to preserve its viability. It is standardized to ensure a consistent concentration of live bacteria, providing reliable and reproducible results for research applications.
Researchers might face challenges such as maintaining the viability of Lactobacillus plantarum powder under different experimental conditions, ensuring accurate dosing, and accounting for strain-specific effects. Additionally, the interpretation of results can be complicated by the complex interactions within the microbiome.
Histopathologic analysis included (a) liver, (b) heart, and (c) spleen sections in male rats
The study evaluated the safety of multiple strains of Lactobacillus plantarum and Pediococcus pentosaceus in Wistar rats through the Ames test and a 28-day feeding study. The strains used were Lactobacillus plantarum HK006 and HK109, and Pediococcus pentosaceus PP31. These probiotics were tested for mutagenic potential using Salmonella Typhimurium strains TA98 and TA1535, both with and without metabolic activation. The results showed no mutagenicity, indicating the probiotic combination is free from mutagenic activity.
In the 28-day feeding study, rats were administered either a normal dosage (390 mg/kg/day) or a high dosage (1950 mg/kg/day) of the probiotic powder. No adverse effects were observed regarding the general condition, behavior, growth, feed and water consumption, hematology, clinical chemistry indices, organ weights, or histopathological analysis. The study concluded that the consumption of these multiple strains of LAB is not associated with any signs of mutagenicity or toxicity in Wistar rats, supporting the safety of these probiotics for potential human use.
Tsai, C. C., Leu, S. F., et al. Safety evaluation of multiple strains of Lactobacillus plantarum and Pediococcus pentosaceus in Wistar rats based on the Ames test and a 28-day feeding study. The Scientific World Journal. 2014, 2014. Distributed under Open Access license CC BY 4.0, without modification.
Click the button below to contact us or submit your feedback about this product.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Copyright © 2024 Creative Biolabs. All Rights Reserved.