Clostridium butyricum is a strictly anaerobic endospore-forming Gram-positive butyric acid-producing bacillus.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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LBST-063FG |
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Product Information | |
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Product Overview | Clostridium butyricum is a strictly anaerobic endospore-forming Gram-positive butyric acid-producing bacillus. |
Target | Clostridium |
Genus | Clostridium |
Application | Study and research |
Type Strain | No |
Culture Medium | Thioglycolate medium |
Culture Conditions | 37°C; Anaerobic |
Risk Group | 1 |
Product Format | Freeze-dried |
Packaging | Ampoule tube |
Storage | -80°C |
Shelf Life | 6 years |
Target Introduction | |
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Introduction | Clostridium is a genus of rod-shaped, usually Gram-positive bacteria, members of which are found in soil, water, and the intestinal tracts of humans and other animals. The majority of species are obligate anaerobes. As the predominant bacteria in gut, Clostridium species exert lots of benefits to body health via interacting with intestine directly or indirectly. Clostridium species are potent candidates to alleviate dysfunctions and disorders in intestine, they have been reported to attenuate inflammation and allergic diseases effectively owing to their distinctive biological activities. Their cellular components and metabolites, like butyrate, secondary bile acids and indolepropionic acid, play a probiotic role primarily through energizing intestinal epithelial cells, strengthening intestinal barrier and interacting with immune system. In view of their salutary performances, Clostridium species have a huge potential as probiotics. |
Alternative Names | Clostridium butyricum; 185375 |
Clostridium butyricum is widely used in research for its probiotic properties and ability to produce butyric acid. It is often applied in studies related to gut health, microbiome interactions, and the production of biofuels and biochemicals. Researchers also explore its potential in enhancing immune function and intestinal barrier integrity.
Culturing Clostridium butyricum involves anaerobic conditions using specific growth media. The bacteria are inoculated in a medium containing nutrients such as glucose or xylose and incubated at optimal temperatures, typically around 37°C. Strict anaerobic techniques, such as using anaerobic chambers or gas packs, are required to maintain the necessary low-oxygen environment.
Clostridium butyricum plays a crucial role in gut microbiome studies due to its ability to produce butyrate, a short-chain fatty acid that supports colon health. It aids in maintaining the intestinal barrier, modulating immune responses, and inhibiting pathogenic bacteria. These properties make it valuable in research focusing on gastrointestinal health and disease prevention.
Clostridium butyricum can be used in co-culture systems with other microorganisms to enhance the production of desired metabolites or study microbial interactions. Co-culturing with complementary species can improve metabolic efficiency, enhance product yields, and provide insights into symbiotic relationships within the microbiome.
Downstream processing of Clostridium butyricum involves several steps, including cell harvesting, purification of metabolites such as butyric acid, and stabilization of the bacterial culture for storage or further use. Techniques such as centrifugation, filtration, and chromatographic methods are commonly employed to achieve high purity and quality of the final products.
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For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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