Clostridium butyricum was isolated from activated sludge. It is a strictly anaerobic endospore-forming Gram-positive butyric acid-producing bacillus.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information
Product Overview
Clostridium butyricum was isolated from activated sludge. It is a strictly anaerobic endospore-forming Gram-positive butyric acid-producing bacillus.
Target
Clostridium
Genus
Clostridium
Strain Designation
INET1
Application
Study and research
Type Strain
Yes
Culture Conditions
37°C; Anaerobic
Source
Activated sludge
Risk Group
1
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
Clostridium is a genus of rod-shaped, usually Gram-positive bacteria, members of which are found in soil, water, and the intestinal tracts of humans and other animals. The majority of species are obligate anaerobes. As the predominant bacteria in gut, Clostridium species exert lots of benefits to body health via interacting with intestine directly or indirectly. Clostridium species are potent candidates to alleviate dysfunctions and disorders in intestine, they have been reported to attenuate inflammation and allergic diseases effectively owing to their distinctive biological activities. Their cellular components and metabolites, like butyrate, secondary bile acids and indolepropionic acid, play a probiotic role primarily through energizing intestinal epithelial cells, strengthening intestinal barrier and interacting with immune system. In view of their salutary performances, Clostridium species have a huge potential as probiotics.
Alternative Names
Clostridium butyricum; 1.2756
FAQs Customer Reviews Related Products
What is the optimal growth condition for Clostridium butyricum?
Clostridium butyricum thrives best in strictly anaerobic conditions with an optimal temperature range of 37°C. This strain requires a nutrient-rich medium that supports the production of butyric acid. To ensure proper growth, maintaining a pH range between 6.0 and 7.5 is crucial. The anaerobic environment can be achieved using anaerobic chambers or specialized media that support low oxygen levels.
How does Clostridium butyricum contribute to gut health?
Clostridium butyricum is widely used in studies related to gastrointestinal health, metabolic diseases, and immune modulation. It is also utilized in research focusing on its role in preventing chemotherapy-induced diarrhea and its potential in treating Clostridium difficile infections. Researchers use this strain to investigate its probiotic effects, including the production of butyric acid and its impact on the gut microbiota.
How is Clostridium butyricum administered in experimental setups?
In research settings, Clostridium butyricum can be administered orally via gavage or mixed into the diet of animal models. For in vitro studies, it is cultured under anaerobic conditions and introduced into cell cultures or gut simulation models to study its effects on gut barrier integrity and immune responses. Proper handling and preparation under anaerobic conditions are essential to maintain the viability and activity of the bacteria.
How should Clostridium butyricum be stored for long-term use?
For long-term storage, Clostridium butyricum can be preserved by freezing at -80°C in a cryoprotectant solution such as 15-20% glycerol. Alternatively, lyophilization (freeze-drying) can be used to store the bacterial cultures at room temperature. These methods ensure the viability of the bacteria for extended periods, allowing for consistent experimental results upon revival.
How is the effectiveness of Clostridium butyricum assessed in research studies?
The effectiveness of Clostridium butyricum in research studies can be assessed using various methods, including measuring butyric acid production, monitoring changes in gut microbiota composition through 16S rRNA sequencing, and evaluating its impact on intestinal health and immune responses. Functional assays such as anti-inflammatory and immunomodulatory assays can also provide insights into the probiotic's effectiveness.
Superior Consistency in Research Clostridium butyricum; 1.2756 from Creative Biolabs ensures consistent results in gut microbiota studies. Its superior anaerobic stability outperforms similar products, making it invaluable for precise research outcomes.
Reliable in Immune Response Studies
This strain demonstrates excellent reliability in immunomodulatory assays. Its consistent performance in stimulating immune responses provides a significant advantage for in vitro research compared to other brands.
High-Quality and Trustworthy
Creative Biolabs' Clostridium butyricum; 1.2756 maintains high viability during experiments, which is crucial for accurate results. This quality makes it a preferred choice for gastrointestinal research studies.
Exceptional in Metabolic Research
The strain's effectiveness in metabolic studies, especially for analyzing short-chain fatty acids production, is remarkable. It has proven more effective than other available options, ensuring reliable data for researchers.
Optimal for Probiotic Research Clostridium butyricum; 1.2756 offers optimal performance in probiotic research, supporting robust growth of beneficial gut bacteria. Its high purity and stability provide an edge over competing products.
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