Clostridium acetobutylicum is a chemoorganotroph. It is a Gram-positive bacillus. It requires anaerobic conditions in order to grow in its vegetative state.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information
Product Overview
Clostridium acetobutylicum is a chemoorganotroph. It is a Gram-positive bacillus. It requires anaerobic conditions in order to grow in its vegetative state.
Target
Clostridium
Genus
Clostridium
Strain Designation
2289
Application
Study and research
Type Strain
Yes
Culture Medium
Blood agar
Culture Conditions
37°C; Anaerobic
Risk Group
1
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
Clostridium is a genus of rod-shaped, usually Gram-positive bacteria, members of which are found in soil, water, and the intestinal tracts of humans and other animals. The majority of species are obligate anaerobes. As the predominant bacteria in gut, Clostridium species exert lots of benefits to body health via interacting with intestine directly or indirectly. Clostridium species are potent candidates to alleviate dysfunctions and disorders in intestine, they have been reported to attenuate inflammation and allergic diseases effectively owing to their distinctive biological activities. Their cellular components and metabolites, like butyrate, secondary bile acids and indolepropionic acid, play a probiotic role primarily through energizing intestinal epithelial cells, strengthening intestinal barrier and interacting with immune system. In view of their salutary performances, Clostridium species have a huge potential as probiotics.
Alternative Names
Clostridium acetobutylicum; 2289
FAQs Customer Reviews Related Products
What are the optimal growth conditions for Clostridium acetobutylicum?
Clostridium acetobutylicum thrives under strict anaerobic conditions with optimal growth temperatures ranging from 30°C to 37°C. The bacterium requires a nutrient-rich medium, typically a modified Reinforced Clostridial Medium (RCM), which provides essential nutrients and maintains the necessary pH for growth.
How is Clostridium acetobutylicum utilized in microbiome studies related to human health?
Clostridium acetobutylicum can be used in microbiome studies to understand its role in gut health and its interactions with other microbial communities. Researchers cultivate this bacterium under anaerobic conditions and monitor its effects on various health markers, including the production of short-chain fatty acids and their impact on gut epithelial cells.
How does Clostridium acetobutylicum contribute to the development of probiotics?
Clostridium acetobutylicum is studied for its potential probiotic properties, particularly its ability to produce butyric acid, which is beneficial for gut health. Researchers cultivate the bacterium in specialized media to optimize butyrate production and assess its impact on intestinal health through in vitro and in vivo studies.
Can Clostridium acetobutylicum be genetically modified for enhanced health benefits?
Yes, genetic modification techniques can be employed to enhance the bacterium's ability to produce health-promoting compounds such as butyrate. Researchers use CRISPR-Cas9 or other genetic engineering tools to introduce or knock out specific genes, optimizing metabolic pathways for increased production of beneficial metabolites.
Outstanding Performance in Metabolic Studies Clostridium acetobutylicum 2289 excels in metabolic pathway research, providing reliable and consistent results. Its robustness in varying conditions makes it superior for detailed biochemical analyses.
Reliable and Reproducible Results
Creative Biolabs' Clostridium acetobutylicum 2289 ensures reproducibility and reliability in experimental setups, which is crucial for advancing pharmaceutical research and developing new therapeutic strategies.
Enhanced Genetic Modification Capabilities
The genetic tractability of Clostridium acetobutylicum 2289 facilitates advanced genetic modifications, enabling innovative research in metabolic engineering and synthetic biology.
High-Quality Product for Advanced Research
Creative Biolabs provides a high-quality Clostridium acetobutylicum 2289 strain that is ideal for cutting-edge research in microbial fermentation and metabolic studies. Their rigorous quality control ensures top-notch performance.
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