Clostridium beijerinckii is a Gram-positive, rod shaped, motile bacterium.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information | |
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Product Overview | Clostridium beijerinckii is a Gram-positive, rod shaped, motile bacterium. |
Target | Clostridium |
Genus | Clostridium |
Application | Study and research |
Type Strain | Yes |
Culture Medium | Blood agar |
Culture Conditions | 37°C; Anaerobic |
Risk Group | 1 |
Product Format | Freeze-dried |
Packaging | Ampoule tube |
Storage | -80°C |
Shelf Life | 6 years |
Target Introduction | |
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Introduction | Clostridium is a genus of rod-shaped, usually Gram-positive bacteria, members of which are found in soil, water, and the intestinal tracts of humans and other animals. The majority of species are obligate anaerobes. As the predominant bacteria in gut, Clostridium species exert lots of benefits to body health via interacting with intestine directly or indirectly. Clostridium species are potent candidates to alleviate dysfunctions and disorders in intestine, they have been reported to attenuate inflammation and allergic diseases effectively owing to their distinctive biological activities. Their cellular components and metabolites, like butyrate, secondary bile acids and indolepropionic acid, play a probiotic role primarily through energizing intestinal epithelial cells, strengthening intestinal barrier and interacting with immune system. In view of their salutary performances, Clostridium species have a huge potential as probiotics. |
Alternative Names | Clostridium beijerinckii; 1.1921 |
Culturing Clostridium beijerinckii requires an anaerobic environment with a temperature of 37°C. The medium should be rich in carbohydrates such as glucose or starch to support its growth and solvent production capabilities. Maintaining a pH of around 6.5 is crucial for optimal growth and metabolic activity
Engineering the metabolic pathways of Clostridium beijerinckii involves genetic modifications to increase the yield of desired metabolites. Techniques such as CRISPR-Cas9 can be employed to knock out genes that divert resources away from target compounds or to introduce new pathways that enhance production. Optimizing co-factor availability and enzyme activity is also a key strategy.
The primary metabolites produced by Clostridium beijerinckii include acetone, butanol, and ethanol. These solvents are crucial in pharmaceutical research as they serve as precursors for various drug formulations.
The production of solvents by Clostridium beijerinckii is quantified using techniques like gas chromatography (GC) and high-performance liquid chromatography (HPLC). These methods accurately measure the concentrations of solvents such as acetone and butanol in the culture medium, providing insights into the metabolic efficiency and production levels.
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For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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