Clostridium leptum is an anaerobe, mesophilic bacterium that was isolated from human faeces. It is a bacterium species in the genus Clostridium.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information | |
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Product Overview | Clostridium leptum is an anaerobe, mesophilic bacterium that was isolated from human faeces. It is a bacterium species in the genus Clostridium. |
Target | Clostridium |
Genus | Clostridium |
Strain Designation | VPI T7-24-1 |
Application | Study and research |
Type Strain | Yes |
Culture Medium | Blood agar |
Culture Conditions | 37°C; Anaerobic |
Source | Human feces |
Risk Group | 1 |
Product Format | Freeze-dried |
Packaging | Ampoule tube |
Storage | -80°C |
Shelf Life | 6 years |
Target Introduction | |
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Introduction | Clostridium is a genus of rod-shaped, usually Gram-positive bacteria, members of which are found in soil, water, and the intestinal tracts of humans and other animals. The majority of species are obligate anaerobes. As the predominant bacteria in gut, Clostridium species exert lots of benefits to body health via interacting with intestine directly or indirectly. Clostridium species are potent candidates to alleviate dysfunctions and disorders in intestine, they have been reported to attenuate inflammation and allergic diseases effectively owing to their distinctive biological activities. Their cellular components and metabolites, like butyrate, secondary bile acids and indolepropionic acid, play a probiotic role primarily through energizing intestinal epithelial cells, strengthening intestinal barrier and interacting with immune system. In view of their salutary performances, Clostridium species have a huge potential as probiotics. |
Alternative Names | Clostridium leptum |
Clostridium leptum should be stored at -80°C for long-term preservation. It is important to maintain the anaerobic environment during storage to ensure viability. For short-term use, the strain can be stored at 4°C in appropriate anaerobic storage media.
To revive Clostridium leptum from frozen stocks, rapidly thaw the vial at 37°C and immediately transfer the contents to an anaerobic growth medium. Incubate the culture under anaerobic conditions at 37°C until significant growth is observed.
The purity and identity of Clostridium leptum are verified using a combination of biochemical tests, 16S rRNA gene sequencing, and molecular methods such as PCR. These techniques ensure the strain is free from contaminants and accurately identified.
Clostridium leptum is frequently used in animal model studies to investigate its role in gut health, immune modulation, and metabolic effects. It has been shown to influence intestinal barrier function and host-microbiome interactions, making it valuable for preclinical research.
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For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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