Bacteroides fragilis was isolated from human blood. It is an anaerobic, Gram-negative, pleomorphic to rod-shaped bacterium.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information
Product Overview
Bacteroides fragilis was isolated from human blood. It is an anaerobic, Gram-negative, pleomorphic to rod-shaped bacterium.
Target
Bacteroides
Genus
Bacteroides
Application
Study and research
Culture Medium
Blood agar
Culture Conditions
37°C; Anaerobic
Source
Human blood
Risk Group
2
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 1% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.
Alternative Names
Bacteroides fragilis; 36926
FAQs Customer Reviews Related Products
What are the necessary steps for handling Bacteroides fragilis to maintain its viability?
When handling Bacteroides fragilis, it is essential to work under anaerobic conditions using an anaerobic chamber or jars. Quick and efficient transfer from storage to culture media minimizes oxygen exposure and maintains viability.
What type of medium is recommended for optimal growth of Bacteroides fragilis?
For optimal growth, Bacteroides fragilis should be cultured in Brain Heart Infusion (BHI) broth supplemented with hemin and vitamin K. This medium supports the specific nutritional requirements of the strain.
What are the specific applications of Bacteroides fragilis in drug development research?
Bacteroides fragilis is instrumental in studying the gut microbiome's role in drug metabolism, immune modulation, and resistance mechanisms. It helps in understanding microbial interactions and their impact on drug efficacy and safety.
What methods are best for confirming the identity of Bacteroides fragilis in research settings?
The identity of Bacteroides fragilis can be confirmed using 16S rRNA gene sequencing and strain-specific PCR assays. These methods ensure the accuracy and purity of the culture used in research.
Remarkable Stability Bacteroides fragilis; 36926 from Creative Biolabs consistently demonstrates remarkable stability, crucial for gut microbiota research. This reliability has significantly enhanced the quality of our experimental results.
Exceptional Purity Levels
The purity levels of Creative Biolabs' Bacteroides fragilis; 36926 are exceptional. This purity has been vital in ensuring accurate outcomes in our immune modulation studies.
Efficient Thaw and Recovery
Thawing and recovering Bacteroides fragilis; 36926 is efficient, saving valuable time in our research workflow. This efficiency is essential for maintaining the integrity of our experiments.
Superior Experimental Reproducibility
Using Bacteroides fragilis; 36926 has significantly improved the reproducibility of our experiments. This strain provides reliable data, critical for our microbiome and drug development research.
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