Bacteroides fragilis was isolated from human blood. It is an anaerobic, Gram-negative, pleomorphic to rod-shaped bacterium.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information
Product Overview
Bacteroides fragilis was isolated from human blood. It is an anaerobic, Gram-negative, pleomorphic to rod-shaped bacterium.
Target
Bacteroides
Genus
Bacteroides
Application
Study and research
Culture Medium
Blood agar
Culture Conditions
37°C; Anaerobic
Source
Human blood, 49-yr-old woman
Risk Group
2
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 1% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.
Alternative Names
Bacteroides fragilis; 49424
FAQs Customer Reviews Related Products
What conditions are necessary for the optimal growth of Bacteroides fragilis in the lab?
Bacteroides fragilis thrives in anaerobic conditions at 37°C using specialized media such as blood agar or BHI agar supplemented with vitamin K and hemin. This setup supports its growth by providing the necessary nutrients and anaerobic environment.
How should Bacteroides fragilis be stored to maintain viability for research purposes?
For long-term storage, Bacteroides fragilis should be kept at -80°C in a suitable cryoprotective medium, such as glycerol-based solutions, to preserve cell integrity and viability over extended periods.
Can Bacteroides fragilis be genetically modified for experimental purposes?
Yes, genetic modification techniques such as CRISPR/Cas9 can be employed with Bacteroides fragilis, allowing researchers to study gene function and regulation under anaerobic conditions. This makes it an excellent model for gastrointestinal research.
How does Bacteroides fragilis contribute to understanding human gut health in research?
Due to its ability to produce important metabolites like short-chain fatty acids and its role in modulating the immune system, Bacteroides fragilis is extensively used in studies investigating the microbiome's impact on gut health and disease, particularly in conditions like inflammatory bowel disease and colorectal cancer.
Robust Performance in Anaerobic Studies
Creative Biolabs' Bacteroides fragilis; 49424 provides unmatched consistency and viability in anaerobic conditions, making it a preferred model in our gastrointestinal research.
Leader in Antibiotic Resistance Research
The strain's resistance profile makes it invaluable for our studies on antibiotic resistance mechanisms, greatly surpassing similar offerings from other companies.
Advanced Genetic Study Tool
Using Bacteroides fragilis; 49424 from Creative Biolabs has advanced our genetic manipulation studies, thanks to its well-documented genome and adaptability.
High-Quality Strain for Pathogenicity Tests
This strain's robustness makes it ideal for our pathogenicity tests, offering reliable and reproducible results that are essential for high-stakes research.
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