Bacteroides thetaiotaomicron is a Gram-negative obligate anaerobe, it is isolated from human. Also, It is one of the most common bacteria found in human gut microbiota.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
CAT
Size
Price
Quantity
LBST-035FG
Product Information
Product Overview
Bacteroides thetaiotaomicron is a Gram-negative obligate anaerobe, it is isolated from human. Also, It is one of the most common bacteria found in human gut microbiota.
Target
Bacteroides
Genus
Bacteroides
Application
Study and research
Type Strain
Yes
Culture Medium
PYG
Culture Conditions
37°C; Anaerobic
Source
Human
Risk Group
1
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 1% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.
Alternative Names
Bacteroides thetaiotaomicron; 28148
FAQs Customer Reviews Related Products
How is genetic stability of B. thetaiotaomicron ensured during experimental manipulation?
Genetic stability can be ensured by minimizing passage number, using cryopreservation for long-term storage, and regularly validating the strain's identity and purity through genetic sequencing. It's also advisable to perform periodic checks for phenotypic consistency across experimental replicates.
Can B. thetaiotaomicron be used in co-culture studies?
Yes, B. thetaiotaomicron is suitable for co-culture studies to explore interactions with other gut microbiota or host cells. It has been used to investigate its effects on the growth and virulence of other pathogens, providing insights into microbial competition and cooperation within the gut ecosystem.
What are the key considerations when designing experiments using B. thetaiotaomicron in animal models?
When using B. thetaiotaomicron in animal models, it's essential to ensure animals are maintained in a germ-free environment prior to inoculation to avoid interactions with other microbiota. Dosage and the method of administration (e.g., oral gavage vs. fecal transplant) should be carefully planned based on the study's objectives.
What methods are recommended for quantifying B. thetaiotaomicron in biological samples?
Quantification of B. thetaiotaomicron can be accurately performed using qPCR with specific primers, targeting unique genetic markers of the strain. This technique is sensitive enough to detect small quantities in diverse sample types, including fecal matter and intestinal tissue.
Unmatched Purity for Research
Creative Biolabs' Bacteroides thetaiotaomicron; 28148 has consistently shown remarkable purity and viability, enhancing reliability in our microbiome research.
Superior Viability Enhances Reproducibility
The superior viability of Bacteroides thetaiotaomicron; 28148 from Creative Biolabs ensures reproducibility in our gastrointestinal models, making it a cornerstone of our studies.
Robust Performance in Host Interaction Studies
In our host-microbe interaction studies, Bacteroides thetaiotaomicron; 28148 has demonstrated robust performance, facilitating insightful discoveries in microbial pathogenesis.
Essential Tool for Gut Microbiota Research
Creative Biolabs' strain has been indispensable for our research into the gut microbiota's role in health and disease, thanks to its stable genetic and phenotypic characteristics.
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