Bacteroides fragilis was isolated from human tube. It is an anaerobic, Gram-negative, pleomorphic to rod-shaped bacterium.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information
Product Overview
Bacteroides fragilis was isolated from human tube. It is an anaerobic, Gram-negative, pleomorphic to rod-shaped bacterium.
Target
Bacteroides
Genus
Bacteroides
Application
Study and research
Culture Medium
Blood agar
Culture Conditions
37°C; Anaerobic
Source
Human tube
Risk Group
2
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 1% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.
Alternative Names
Bacteroides fragilis; 35671
FAQs Customer Reviews Related Products
How should Bacteroides fragilis be cultured for laboratory experiments?
To effectively culture Bacteroides fragilis, it is critical to use anaerobic conditions. The culture media should be pre-reduced and maintained at an appropriate temperature, generally 37°C, to support optimal growth.
How should Bacteroides fragilis be stored for long-term viability?
For long-term storage, Bacteroides fragilis should be kept at -80°C in an anaerobic glycerol broth. This method helps preserve the bacterial cells' integrity and functionality for future experimental use.
How can genetic manipulation be performed on Bacteroides fragilis in research settings?
Genetic manipulation of Bacteroides fragilis requires specialized vectors and techniques such as electroporation or conjugation. Use antibiotic resistance markers for selection and ensure all procedures are done under strictly anaerobic conditions to maintain viability.
What are the quality control measures for ensuring the purity and activity of Bacteroides fragilis cultures?
Implement regular testing for contaminants using selective media and molecular techniques such as PCR. Additionally, verify the functional activity of the strain through assays that confirm its capability to produce key metabolites or exhibit desired phenotypic traits.
Efficient Strain for Gut Health Studies
Creative Biolabs' Bacteroides fragilis; 35671 exhibits outstanding adaptability and robustness in in-vitro experiments, making it invaluable for studying gut-related disorders.
Leader in Genetic Manipulation
The genetic manipulability of Bacteroides fragilis; 35671 allows for intricate studies on gene expression and regulation, essential for our advanced microbial therapy research.
Robust in Anaerobic Growth Conditions
Creative Biolabs' Bacteroides fragilis; 35671 thrives exceptionally under anaerobic conditions, providing reliable results in our gastrointestinal microbiota studies.
Innovative Probiotic Applications Bacteroides fragilis's unique properties, such as SCFA production and mucosal barrier reinforcement, have broadened the scope of our therapeutic research.
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