Bacteroides vulgatus is generally considered to be a beneficial gut commensal.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
CAT
Size
Price
Quantity
LBST-023FG
Product Information
Product Overview
Bacteroides vulgatus is generally considered to be a beneficial gut commensal.
Target
Bacteroides
Genus
Bacteroides
Application
Study and research
Type Strain
Yes
Culture Medium
Blood agar
Culture Conditions
37°C; Anaerobic
Characteristics
Strictly anaerobic
Risk Group
2
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 1% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.
Alternative Names
Bacteroides vulgatus; 8482
FAQsPublished Data Customer Reviews Related Products
How should Bacteroides vulgatus be prepared for experimental use?
Thaw Bacteroides vulgatus rapidly in a 37°C water bath. Once thawed, immediately transfer the bacteria to an anaerobic chamber to avoid oxygen exposure. Pre-reduced media and equipment should be used to maintain anaerobic conditions.
What type of medium is recommended for culturing Bacteroides vulgatus?
Bacteroides vulgatus thrives in pre-reduced anaerobically sterilized (PRAS) media. It is crucial to use media that supports anaerobic bacterial growth to ensure optimal proliferation and viability of the culture.
What are the common applications of Bacteroides vulgatus in research?
Bacteroides vulgatus is frequently used in studies of gut microbiota dynamics, metabolic interactions, and inflammatory responses. Its role in these processes makes it a valuable model for exploring microbial influences on health.
How is the purity of Bacteroides vulgatus verified?
The purity of Bacteroides vulgatus is verified through a series of quality control tests, including genetic sequencing and microbial purity assessments. These tests ensure the strain is free from contaminants and genetically consistent with reference standards.
Relative abundance of B4PC2 community in cecum of gnotobiotic mice
The study focuses on the in vivo lifestyle of bile acid 7α-dehydroxylating bacteria, specifically analyzing the transcriptional responses of Clostridium hylemonae and Clostridium hiranonis in gnotobiotic mice. Bacteroides vulgatus 8482, part of a defined microbial community, plays a significant role in bile acid metabolism. The experiment involved colonizing germ-free mice with bacterial isolates and analyzing bile acid metabolomics. The results showed that Bacteroides vulgatus, along with other community members, effectively deconjugated bile acids and contributed to secondary bile acid formation. This indicates the potential of Bacteroides vulgatus in influencing host bile acid composition and highlights its role in microbial bile acid metabolism. The experimental data demonstrated that Bacteroides vulgatus made up 39.06% of the cecal reads, showing its dominant presence. The bile acid metabolomics revealed significant conversion of primary bile acids to secondary bile acids, with deoxycholic acid (DCA) constituting 27.1% of total bile acids in the cecum. This underscores the functional impact of Bacteroides vulgatus and other community members on bile acid metabolism, providing insights into the interactions between gut microbiota and host bile acid composition.
Ridlon, Jason M., et al. "The in vivo lifestyle'of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice." Gut microbes 11.3 (2020): 381-404.
Outstanding Stability and Viability Bacteroides vulgatus; 8482 from Creative Biolabs has shown remarkable stability and viability in our gut microbiota studies. Its consistent performance has significantly enhanced the reliability of our research outcomes.
Reliable Performance in Inflammatory Research
Using Bacteroides vulgatus; 8482 has been instrumental in our inflammatory bowel disease studies. Creative Biolabs' rigorous quality control ensures dependable and accurate data, making it superior to other options.
Ideal for Microbial Dynamics Research Bacteroides vulgatus; 8482 excels in microbial dynamics studies. Its excellent viability and genetic stability provided by Creative Biolabs make it a top choice for our experiments.
Consistent Results in Microbiome Studies
Creative Biolabs delivers top-notch Bacteroides vulgatus; 8482 with excellent service. The strain's purity and viability have markedly improved our microbiome research, providing reliable and reproducible data.
Unmatched Quality for Research Applications Bacteroides vulgatus; 8482 from Creative Biolabs is unmatched in quality. Its stable and reliable performance has been critical in our research, setting a new standard for excellence in microbial studies.
Click the button below to contact us or submit your feedback about this product.
