Bacteroides thetaiotaomicron was isolated from suckling pig feces. It is a Gram-negative obligate anaerobe.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information
Product Overview
Bacteroides thetaiotaomicron was isolated from suckling pig feces. It is a Gram-negative obligate anaerobe.
Target
Bacteroides
Genus
Bacteroides
Strain Designation
Sbu-1
Application
Study and research
Type Strain
No
Culture Conditions
37°C; Facultative anaerobic
Source
Suckling pig feces
Risk Group
1
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 1% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.
Alternative Names
Bacteroides thetaiotaomicron
FAQs Customer Reviews Related Products
How should Bacteroides thetaiotaomicron be cultured to ensure optimal growth?
To culture Bacteroides thetaiotaomicron effectively, use an anaerobic growth medium and maintain the culture at 37°C in an oxygen-free environment. Regular monitoring and medium refreshment are crucial for sustained growth.
Can Bacteroides thetaiotaomicron be used in co-culture systems? What are the considerations?
Yes, Bacteroides thetaiotaomicron can be used in co-culture systems to study microbial interactions. It is vital to balance nutrient supply and maintain anaerobic conditions to reflect the natural gut environment effectively.
What are the common applications of Bacteroides thetaiotaomicron in gastrointestinal research?
This strain is extensively used to investigate host-microbe interactions, particularly its role in metabolizing complex carbohydrates and influencing the host's immune system, making it valuable for studies on gut health and disease.
Is there a recommended protocol for genetic manipulation of Bacteroides thetaiotaomicron?
Genetic manipulation of Bacteroides thetaiotaomicron requires specific tools like CRISPR/Cas9 adapted for anaerobic bacteria. It's advisable to consult detailed protocols focusing on gene editing in anaerobic conditions to ensure successful modifications.
Exceptional Consistency for Gut Microbiota Studies
Creative Biolabs' Bacteroides thetaiotaomicron has shown unparalleled consistency in results for gut microbiota research, significantly outperforming similar strains from other suppliers.
Superior Viability in Anaerobic Conditions
This strain's robust viability under anaerobic conditions makes it indispensable for in-depth studies on anaerobic bacteria and their interactions within the gut.
Advantageous for Metabolic Research
The strain has provided key insights into the metabolism of complex carbohydrates, proving more effective than other commercial strains.
Critical for Immune System Interaction Studies
Utilizing this strain has allowed us to explore previously unidentified interactions between gut microbiota and the immune system, thanks to its high adaptability and genetic stability.
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