Datasheet

Bacteroides vulgatus (CAT#: LBST-025FG)

Bacteroides vulgatus was isolated from human feces. It is generally considered to be a beneficial gut commensal.

For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.

CAT	Size	Price	Quantity
LBST-025FG

Product Information
Product Overview	Bacteroides vulgatus was isolated from human feces. It is generally considered to be a beneficial gut commensal.
Target	Bacteroides
Genus	Bacteroides
Application	Study and research
Type Strain	No
Culture Medium	Columbia blood agar
Culture Conditions	37°C; Anaerobic
Source	Human feces
Risk Group	2
Product Format	Freeze-dried
Packaging	Ampoule tube
Storage	-80°C
Shelf Life	6 years

Target Introduction
Introduction	Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 1% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.
Alternative Names	Bacteroides vulgatus

Target Introduction

Introduction

Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 1% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.

Alternative Names

Bacteroides vulgatus

FAQs Published Data Customer Reviews Related Products

What are the main research applications of Bacteroides vulgatus from Creative Biolabs?
Bacteroides vulgatus is primarily utilized in studying the gut microbiome's role in various health conditions, including inflammatory bowel disease, colorectal cancer, and other gastrointestinal disorders. Researchers can use this strain to explore microbial interactions, resistance mechanisms, and therapeutic potentials.
How is Bacteroides vulgatus cultured and stored for optimal viability?
Creative Biolabs recommends culturing Bacteroides vulgatus under anaerobic conditions at 37°C. For storage, freeze-drying or cryopreservation techniques are advised to maintain viability. Researchers should refer to the provided guidelines for specific media and growth conditions to ensure strain stability.
Can Bacteroides vulgatus be used in co-culture systems?
Yes, Bacteroides vulgatus can be effectively used in co-culture systems to study its interaction with other gut microbiota or host cells. This allows for a deeper understanding of its role in the microbial ecosystem and its effects on host physiology and pathophysiology.
How does Bacteroides vulgatus from Creative Biolabs differ from other commercial strains?
Bacteroides vulgatus from Creative Biolabs is characterized by its high purity and genetic stability, making it a reliable choice for complex microbiological studies. The strain is quality-checked for specific pathogens to ensure safety and reproducibility in research settings.
Is there support available for troubleshooting issues with Bacteroides vulgatus in experimental setups?
Creative Biolabs provides comprehensive technical support for researchers using Bacteroides vulgatus. This includes assistance with culture optimization, troubleshooting growth issues, and advice on experimental design to maximize the reliability and relevance of research outcomes.

Bacteroides-vulgatus-1

Effect of B. vulgatus Bv46 on the DSS-induced colitis in C57BL/6J mice

The study focuses on Bacteroides vulgatus strain Bv46 and its impact on colitis in mice induced by dextran sodium sulfate (DSS). Bacteroides vulgatus is recognized for its prevalent role in the human gut microbiome, and particular strains have been identified for their health benefits, including the modulation of gut microbiota and immune responses. This study highlighted the strain Bv46, administered to mice, which resulted in significant alleviation of colitis symptoms. The therapeutic effects included reduced disease activity, prevention of colon shortening, and less histopathological damage.
Experimentally, Bv46 was shown to modulate the gut microbiota composition significantly. It increased the abundance of beneficial bacterial genera like Parabacteroides and Bacteroides, and enhanced the production of short-chain fatty acids (SCFAs), particularly butyric acid, which is known for its anti-inflammatory properties. The strain also reduced the expression of pro-inflammatory cytokines TNF-a, IL-1b, and IL-6 in colon tissues, demonstrating a direct immunomodulatory effect. Overall, this study presents Bacteroides vulgatus Bv46 as a promising agent for the prevention and management of colitis, highlighting its potential role in therapeutic interventions against inflammatory bowel diseases.

Liu, L., Xu, M., et al. Bacteroides vulgatus attenuates experimental mice colitis through modulating gut microbiota and immune responses. Frontiers in Immunology. 2022, 13: 1036196. Distributed under Open Access license CC BY 4.0, without modification.

Unmatched Research Tool
Creative Biolabs' Bacteroides vulgatus is invaluable for our gut microbiota research, showing superior reproducibility and robustness compared to other products.
Precision in Pathogenesis Studies
The precision that Bacteroides vulgatus from Creative Biolabs offers in our pathogenesis models is unmatched, providing clear insights into microbial-host interactions.
Reliable for Critical Research
We rely on the Bacteroides vulgatus strain from Creative Biolabs for critical gut-brain axis studies; its reliability is fundamental to our success.
Top Choice for Gut Microbiota Research
Creative Biolabs' Bacteroides vulgatus has proven to be a top choice for our research on antibiotic resistance, outperforming alternatives in both growth and genetic fidelity.
Superior Quality and Support
Creative Biolabs' Bacteroides vulgatus not only offers superior quality but also comes with expert support that enhances our research capabilities in inflammatory diseases.

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For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.