The concept of probiotics has traditionally focused on gut health. However, emerging research highlights the critical role of the respiratory microbiome in maintaining health and influencing disease progression. Intranasal and inhalation administration of probiotics offers a direct, non-invasive, and highly targeted approach to modulate the microbial environment of the nasal passages, sinuses, and lungs, or to achieve systemic effects by bypassing first-pass metabolism. This innovative delivery method holds immense promise for addressing conditions ranging from respiratory infections and allergies to neurological disorders via the gut-brain axis, and even systemic inflammatory diseases. Our expert team and state-of-the-art facilities are equipped to design and execute robust preclinical studies, providing invaluable data to advance your probiotic product development.
Animal Models
Animal Model Selection: Expert guidance on choosing the most appropriate animal species (e.g., mice, rats, guinea pigs, rabbits) and disease models (e.g., allergic asthma, COPD, influenza infection, bacterial pneumonia, sinusitis, neuroinflammatory models).
Sample Information
To facilitate accurate proposal development and study design, please provide the following information:
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Probiotic Strain Details: Full strain name (genus, species, strain designation), source, purity, viability data, and storage conditions.
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Desired Formulation: Preferred delivery vehicle (e.g., saline, specific excipients), concentration, and volume per dose.
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Target Indication/Disease Model: Specific disease or condition you wish to investigate and any preferred animal models.
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Research Objectives: Clearly state the primary and secondary objectives of the research.
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Key Endpoints of Interest: Specific measurements you wish to obtain (e.g., inflammatory markers, microbiome changes, pathogen reduction, behavioral improvements).
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Preliminary Data (if available): Any in vitro or pilot in vivo data.
Turnaround Time
The timing of the research depends on the complexity of the experimental design, the animal model, and the types of evaluation indicators. However, we strive for efficient project completion. We will provide a detailed timeline specific to your project in our proposal.
Ready to explore the potential of intranasal/inhalation probiotic delivery for your product? Contact us today to schedule a confidential consultation with our scientific experts. Let us help you accelerate your research and bring innovative probiotic therapies to market.
