Adlercreutzia equolifaciens is an anaerobe, mesophilic, Gram-positive Actinobacterium that was isolated from human faeces.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information
Product Overview
Adlercreutzia equolifaciens is an anaerobe, mesophilic, Gram-positive Actinobacterium that was isolated from human faeces.
Target
Eggerthellaceae
Genus
Adlercreutzia
Application
Study and research
Culture Medium
BHI agar; Chocolate agar
Culture Conditions
37°C; Anaerobic
Source
Human feces, 25-yr-old healthy woman
Risk Group
1
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
The Eggerthellaceae are a family of Gram-positive, rod- or coccus-shaped Actinobacteria. It is the sole family within the order Eggerthellales. Members of this family are mostly anaerobic, non-motile, asaccharolytic and do not form spores. Eggerthellaceae species are commonly isolated from human and animal faeces and other human sources such as the colon, vagina, oral cavity and blood.
Alternative Names
Adlercreutzia equolifaciens
FAQsPublished Data Customer Reviews Related Products
How is Adlercreutzia equolifaciens utilized in probiotic development research?
Adlercreutzia equolifaciens is extensively utilized in probiotic development research due to its ability to produce equol, a metabolite known for its beneficial effects on human health. Researchers study this bacterium to enhance the production of equol, which is linked to improved gut health and potential protective effects against various diseases.
What are the optimal growth conditions for Adlercreutzia equolifaciens in the laboratory?
Adlercreutzia equolifaciens thrives in an anaerobic environment with a temperature range of 37°C. The growth medium should be supplemented with specific nutrients to support its metabolic activities. Maintaining pH levels between 6.5 and 7.5 is also crucial for optimal growth.
What methodologies are used to isolate and identify Adlercreutzia equolifaciens in clinical samples?
Isolation of Adlercreutzia equolifaciens involves anaerobic culturing techniques using selective media. Identification is typically achieved through 16S rRNA gene sequencing, which provides accurate taxonomic placement within the gut microbiota.
How does Adlercreutzia equolifaciens interact with other gut microbiota in probiotic development?
Adlercreutzia equolifaciens interacts synergistically with other gut microbiota, enhancing the overall metabolic output and stability of the gut ecosystem. It can improve the colonization and functionality of other beneficial bacteria, contributing to a balanced microbiome.
The genetic organization of upstream and downstream ORFs flanking the equol gene cluster in A. equolifaciens
This study explores the metabolism of soy isoflavones by intestinal bacteria, focusing on the genome analysis of Adlercreutzia equolifaciens, a known equol producer. The researchers isolated 73 fecal bacteria strains from equol-producing women and tested their ability to convert daidzein and genistein into their metabolites. While several strains produced dihydrodaidzein and O-desmethylangolensin (O-DMA) from daidzein and dihydrogenistein from genistein, no equol producers were identified, despite the presence of A. equolifaciens W18.34a, a species known for equol production. Genome analysis revealed that A. equolifaciens W18.34a lacked a significant portion of the equol operon, explaining its inability to produce equol. This deletion was compared with other strains, showing variations in equol-related gene presence. The study underscores the complex role of gut bacteria in isoflavone metabolism, highlighting the need for further research to fully understand microbial interactions and their implications for health. The findings suggest that equol production may depend on the presence of specific gene clusters, which can be absent in certain strains, impacting their metabolic capabilities.
Vázquez, Lucía, et al. "Metabolism of soy isoflavones by intestinal bacteria: Genome analysis of an Adlercreutzia equolifaciens strain that does not produce equol." Biomolecules 10.6 (2020): 950. Distributed under Open Access license CC BY 4.0, without modification.
Outstanding Research Consistency
The Adlercreutzia equolifaciens strain offers unparalleled consistency in gut microbiota research. Its reliable performance enhances the validity of experimental results, surpassing other available products.
High Efficiency in Anaerobic Cultures
This product's high efficiency in anaerobic cultures significantly advances probiotic development research. Its superior growth rate and stability are commendable.
Reliable for Gut Microbiome Studies
Creative Biolabs' Adlercreutzia equolifaciens is highly reliable for gut microbiome studies. Its exceptional viability and stability ensure accurate and reproducible results in all experiments.
Optimal for Probiotic Formulation Research
This strain is optimal for research on probiotic formulations. Its ability to thrive in varied conditions provides valuable insights, making it a preferred choice for researchers.
Top Choice for Hormonal Research
Creative Biolabs' Adlercreutzia equolifaciens is the top choice for hormonal research. Its efficient equol production is crucial for developing new therapeutic strategies, making it superior to competitors.
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