The Eggerthellaceae is a family of Gram-positive, rod- or coccus-shaped Actinobacteria. It is the sole family within the order Eggerthellales.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information
Product Overview
The Eggerthellaceae is a family of Gram-positive, rod- or coccus-shaped Actinobacteria. It is the sole family within the order Eggerthellales.
Target
Eggerthellaceae
Genus
Eggerthella
Strain Designation
zg-1050
Application
Study and research
Type Strain
Yes
Culture Conditions
37°C; Anaerobic
Risk Group
1
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
The Eggerthellaceae are a family of Gram-positive, rod- or coccus-shaped Actinobacteria. It is the sole family within the order Eggerthellales. Members of this family are mostly anaerobic, non-motile, asaccharolytic and do not form spores. Eggerthellaceae species are commonly isolated from human and animal faeces and other human sources such as the colon, vagina, oral cavity and blood.
Alternative Names
Eggerthellaceae sp.
FAQsPublished Data Customer Reviews Related Products
How is Eggerthellaceae sp. utilized in probiotic development research?
Eggerthellaceae sp. is extensively utilized in probiotic development research due to its ability to modulate gut microbiota and enhance gastrointestinal health. Researchers employ this bacterium to study its impact on gut flora balance, contributing to the development of effective probiotic formulations aimed at improving human health.
What are the optimal growth conditions for Eggerthellaceae sp. in probiotic development research?
Eggerthellaceae sp. thrives in anaerobic conditions with a temperature range of 37°C, which aligns with the human body temperature. For media, a rich anaerobic medium supplemented with necessary growth factors is recommended. Consistent pH levels and absence of oxygen are crucial for optimal growth.
How can Eggerthellaceae sp. be incorporated into probiotic formulations for human health research?
Incorporating Eggerthellaceae sp. into probiotic formulations involves lyophilization to preserve viability. It is essential to ensure that the bacterial strain is compatible with other probiotic strains and stable during storage. Proper encapsulation techniques can enhance survival through the gastrointestinal tract.
How is the genomic DNA of Eggerthellaceae sp. extracted for genetic analysis?
The genomic DNA of Eggerthellaceae sp. can be extracted using standard bacterial DNA extraction kits. An initial mechanical disruption step followed by enzymatic lysis is recommended to ensure complete cell wall breakdown. Purity and concentration of the extracted DNA should be checked using spectrophotometry.
What challenges are associated with culturing Eggerthellaceae sp. in a laboratory setting?
Culturing Eggerthellaceae sp. presents challenges such as maintaining strict anaerobic conditions and preventing contamination. Additionally, the slow growth rate requires extended incubation periods. Optimizing media composition and maintaining stable environmental conditions are essential for successful cultivation.
Bacterial families associated with pediatric UC ranked according to their statistical significance and heatmap using the (A) 16S, (B) shotgun profiling data
This study analyzed the gut microbiome differences between pediatric ulcerative colitis (UC) patients and healthy controls using both 16S rRNA gene sequencing and metagenomic shotgun sequencing. Involving 19 UC patients and 23 healthy children, the research found that UC patients had significantly lower alpha diversity, indicating a less diverse gut microbial population. Additionally, the beta diversity within UC patients was more variable compared to healthy controls. Key findings highlighted the depletion of microbial families such as Akkermansiaceae, Clostridiaceae, Eggerthellaceae, Lachnospiraceae, and Oscillospiraceae in UC patients. The study also demonstrated that both 16S rRNA and shotgun sequencing data could predict UC status with high accuracy, achieving an AUROC close to 0.90. The depletion of Eggerthellaceae and other families underscores significant microbial shifts in pediatric UC, offering potential markers for early diagnosis and targeted treatment strategies.
Zuo, Wenxuan, et al. "16S rRNA and metagenomic shotgun sequencing data revealed consistent patterns of gut microbiome signature in pediatric ulcerative colitis." Scientific reports 12.1 (2022): 6421. Distributed under Open Access license CC BY 4.0, without modification.
Outstanding Stability
The Eggerthellaceae sp. product demonstrates outstanding stability in anaerobic conditions, making it perfect for probiotic research. Its consistency surpasses similar products.
Exceptional Viability
Creative Biolabs' Eggerthellaceae sp. boasts exceptional viability, maintaining high cell counts throughout research trials. This reliability significantly benefits probiotic formulation studies.
High Purity
The high purity of the Eggerthellaceae sp. product ensures minimal contamination risks, a critical factor in probiotic development.
Enhanced Metabolic Research
Using Eggerthellaceae sp. significantly enhanced metabolic pathway studies. The strain's ability to interact with other microbiota was superior, providing deeper insights into gut health and probiotic efficacy.
Robust Experimental Results
Creative Biolabs' Eggerthellaceae sp. offers robust experimental results, essential for detailed probiotic research. Its reliability and consistency make it a preferred choice for advanced human health studies.
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