Bifidobacterium bifidum is a Gram-positive, anaerobic bacterium that is neither motile nor spore-forming. The bacterium is rod-shaped and can be found living in clusters, pairs, or even independently. It is an essential bacteria found in the human intestine.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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LBST-052FG |
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Product Information | |
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Product Overview | Bifidobacterium bifidum is a Gram-positive, anaerobic bacterium that is neither motile nor spore-forming. The bacterium is rod-shaped and can be found living in clusters, pairs, or even independently. It is an essential bacteria found in the human intestine. |
Target | Bifidobacterium |
Genus | Bifidobacterium |
Strain Designation | 212A |
Application | Study and research |
Type Strain | No |
Culture Medium | BBL |
Culture Conditions | 37°C; Anaerobic |
Risk Group | 1 |
Product Format | Freeze-dried |
Packaging | Ampoule tube |
Storage | -80°C |
Shelf Life | 6 years |
Target Introduction | |
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Introduction | Bifidobacterium are Gram-positive, heterofermentative, anaerobic bacteria with a distinctive bifid; i.e. Y shape after which they are named. They are originally isolated from the faeces of breast-fed infants, members of the genus Bifidobacterium are commonly found in the GI tract of mammals. In humans, Bifidobacterium resides within the GI tract, from birth to old age. Disturbances in the microbiota are linked to an ever-growing number of immune-linked disease states including IBD, atopic allergy, arthritis, and obesity. Therefore, there is a significant interest in treating these diseases through microbial or "probiotic" supplementation of patients, including Bifidobacterium. Data from mouse models and clinical trials indicate that Bifidobacterium may have beneficial effects for treating and preventing immune-linked diseases, including gut-associated and systemic conditions. Bifidobacterium have been commercially exploited as probiotic agents due to their associated health benefits and GRAS; Generally Recognised As Safe status. |
Alternative Names | Bifidobacterium bifidum; 11863 |
The optimal growth conditions typically include anaerobic environments supplemented with specific growth media tailored for Bifidobacterium species. For more detailed protocols, refer to scientific literature on microbiological cultivation methods.
Bifidobacterium bifidum can be stored at ultra-low temperatures (-80°C) or in specialized cryopreservation solutions to maintain viability and functionality over extended periods.
Bifidobacterium bifidum is extensively studied for its potential in gastrointestinal health, immune modulation, and probiotic therapy. Research focuses include its effects on gut microbiota composition, inflammation modulation, and therapeutic applications in gastrointestinal disorders.
Molecular techniques such as PCR (Polymerase Chain Reaction), metagenomics, and transcriptomics are frequently employed to analyze gene expression, microbial community dynamics, and functional pathways influenced by Bifidobacterium bifidum in experimental models.
Animal models like rodent models of colitis or In vitro assays mimicking gut conditions are commonly used to assess the efficacy of Bifidobacterium bifidum in modulating immune responses, intestinal barrier function, and disease outcomes.
Gel Electrophoresis of Lactobacillus acidophilus and Bifidobacterium bifidum gene amplification
The research explores the application of Bifidobacterium bifidum; 11863 in pharmaceutical research, emphasizing its significance through experimental data. The study investigates the probiotic's potential therapeutic benefits, particularly in enhancing gastrointestinal health and modulating immune responses. Experimental findings highlight its ability to regulate gut microbiota composition, demonstrating reduced inflammation and improved intestinal barrier function in animal models. Moreover, the research underscores Bifidobacterium bifidum; 11863's role in mitigating symptoms associated with inflammatory bowel diseases, such as colitis, through its anti-inflammatory properties and promotion of mucosal integrity. These findings suggest promising avenues for developing novel therapeutic strategies harnessing probiotics to target gastrointestinal disorders effectively, thereby advancing clinical applications in digestive health and immune modulation.
Ashour, Zeinab, et al. "Potential impact of gut Lactobacillus acidophilus and Bifidobacterium bifidum on hepatic histopathological changes in non-cirrhotic hepatitis C virus patients with different viral load." Gut Pathogens 14.1 (2022): 25. Distributed under Open Access license CC BY 4.0, without modification.
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For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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