Bacteroides fragilis was isolated from appendix abscess. It is an anaerobic, Gram-negative, pleomorphic to rod-shaped bacterium.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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Size
Price
Quantity
LBST-013FG
Product Information
Product Overview
Bacteroides fragilis was isolated from appendix abscess. It is an anaerobic, Gram-negative, pleomorphic to rod-shaped bacterium.
Target
Bacteroides
Genus
Bacteroides
Strain Designation
VPI 2553
Application
Media testing; Quality control strain; Susceptibility testing; Quality control strain for BBL and MicroScan.
Culture Medium
Columbia blood agar
Culture Conditions
37°C; Anaerobic
Source
Appendix abscess
Risk Group
2
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 1% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.
Alternative Names
Bacteroides fragilis; VPI 2553
FAQsPublished Data Customer Reviews Related Products
What are the ideal culture conditions for Bacteroides fragilis VPI 2553?
This strain should be cultured at 37°C in anaerobic conditions. The recommended medium is chopped meat medium, which can include ground beef, casitone, and other components such as ethanol, K2HPO4, yeast extract, and L-Cysteine HCl, among optional supplements like haemin and vitamins K1 and K3.
Are there specific indicators to monitor the health and viability of Bacteroides fragilis VPI 2553 cultures?
The health and viability of Bacteroides fragilis VPI 2553 can be monitored by observing the colony morphology and growth rate on solid media, and by checking for turbidity and metabolic activity in liquid cultures. Any deviation from typical growth patterns should be investigated.
Can Bacteroides fragilis VPI 2553 be used in co-culture experiments with other gut microbiota?
Yes, Bacteroides fragilis VPI 2553 can be used in co-culture experiments to study interactions within the gut microbiota. It is important to select compatible growth conditions that support both B. fragilis VPI 2553 and other microbial species being studied
What are the primary research applications of Bacteroides fragilis VPI 2553?
Bacteroides fragilis VPI 2553 is used predominantly in media testing, quality control, and antimicrobial susceptibility testing. Its robust adaptability in the human gut also makes it a candidate for studies related to the gut microbiota and its potential probiotic properties.
Can Bacteroides fragilis VPI 2553 be genetically modified for research?
While genetic modification of Bacteroides fragilis VPI 2553 is possible, it must be conducted under strict regulatory compliance. Researchers should ensure that all modifications are ethically justified and legally permitted, with a thorough understanding of the genetic tools and techniques applicable to anaerobic bacteria.
The distribution characteristics of the urine bacterial genus
This study investigates the role of Bacteroides fragilis strain VPI 2553 in the encrustation of ureteral stents, identifying potential bacterial contributions to this common complication in urinary stents. The research utilized 16s DNA tests on urine samples from patients with and without stent encrustations to analyze differences in bacterial flora. Findings indicated a higher prevalence of Bacteroides fragilis in the urine of patients with stent encrustation compared to those without, suggesting a possible link between this bacteria and stent complications. An animal model was then employed to further explore the role of Bacteroides fragilis VPI 2553. Rats were implanted with bladder foreign bodies and subjected to bacterial inoculation. The results showed a significantly higher rate of encrustation in the group exposed to Bacteroides fragilis compared to the control group, reinforcing the hypothesis that Bacteroides fragilis contributes to the development of stent encrustation. This research underscores the importance of managing bacterial colonization to mitigate stent encrustation, proposing potential avenues for clinical interventions to improve stent designs and patient outcomes.
Li, X., Gao, H., et al. A preliminary study on the role of Bacteroides fragilis in stent encrustation. World Journal of Urology. 2021, 39: 579-588.
Superior Quality for Advanced Research
Creative Biolabs' Bacteroides fragilis; VPI 2553 has proven essential for our advanced immunology studies, providing consistent and reliable results, setting it apart from competitors.
Unparalleled Performance
The Bacteroides fragilis; VPI 2553 strain from Creative Biolabs offers unparalleled genetic stability, which crucially enhances the reproducibility of our gastrointestinal research.
Leading Choice for Microbial Studies
For cutting-edge microbial interaction studies, Creative Biolabs' Bacteroides fragilis; VPI 2553 is the leading choice, thanks to its robust growth and genetic fidelity.
Trusted for Consistency
The Bacteroides fragilis; VPI 2553 strain from Creative Biolabs delivers unmatched consistency and viability, making it a trusted resource in our pharmacological research.
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