Parabacteroides goldsteinii was isolated from human wound. It is a Gram-negative, obligately anaerobic non-spore-forming and non-motile bacterium.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information | |
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Product Overview | Parabacteroides goldsteinii was isolated from human wound. It is a Gram-negative, obligately anaerobic non-spore-forming and non-motile bacterium. |
Target | Parabacteroides |
Genus | Parabacteroides |
Application | Study and research |
Culture Medium | Chocolate agar |
Culture Conditions | 37°C; Anaerobic |
Source | Human wound, 65-yr-old female |
Risk Group | 2 |
Product Format | Freeze-dried |
Packaging | Ampoule tube |
Storage | -80°C |
Shelf Life | 6 years |
Target Introduction | |
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Introduction | Parabacteroides is a Gram-negative, anaerobic, non-spore-forming genus from the family Tannerellaceae. Currently, the genus Parabacteroides includes eight valid species with standing in nomenclature. The species Parabacteroides faecis and Parabacteroides johnsonii; faeces and Parabacteroides gordonii; blood were all isolated for the first time in humans. Of all the species, Parabacteroides distasonis is the reference type strain for the genus Parabacteroides. To date, Parabacteroides distasonis has been shown to have beneficial effects on colorectal cancer. Multiple researchers have identified that levels of Parabacteroides distasonis in stool are inversely correlated to the presence of intestinal tumors. The evidence for the potential anti-inflammatory effects of Parabacteroides distasonis in colorectal cancer is further supported by the inverse correlation between Parabacteroides distasonis levels and IL-1β production in the gut, suggesting that Parabacteroides distasonis has anti-tumorigenic and anti-inflammatory potential in colorectal cancer patients. Further potential benefits of Parabacteroides distasonis have been identified, particularly in relation to obesity. In addition, several studies have suggested that Parabacteroides distasonis may play a role in various forms of autoimmunity. |
Alternative Names | Parabacteroides goldsteinii; 74546 |
Use anaerobic basal media supplemented with appropriate nutrients such as peptides, amino acids, and vitamins. Adjust pH to optimal conditions (typically pH 7.0-7.5) to support robust growth and maintain culture viability.
Parabacteroides goldsteinii is believed to modulate host immune responses and metabolic functions by producing beneficial metabolites and interacting with other gut microbes. These mechanisms are crucial in understanding its potential therapeutic applications.
It is advised to store Parabacteroides goldsteinii cultures at -80°C in a dedicated freezer to maintain viability and stability over extended periods. Regularly verify freezer conditions to ensure optimal storage.
Regularly perform microscopic examinations and biochemical tests to confirm the identity of Parabacteroides goldsteinii cultures. Additionally, molecular techniques like PCR can validate species-specific genetic markers.
Conduct experiments under controlled anaerobic conditions to mimic the gut environment. Co-culture Parabacteroides goldsteinii with host cells in vitro and monitor interactions using relevant assays for immune response and metabolic activity.
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For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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