Parabacteroides goldsteinii was isolated from caecal content. It is a Gram-negative, obligately anaerobic non-spore-forming and non-motile bacterium.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information
Product Overview
Parabacteroides goldsteinii was isolated from caecal content. It is a Gram-negative, obligately anaerobic non-spore-forming and non-motile bacterium.
Target
Parabacteroides
Genus
Parabacteroides
Strain Designation
BS-C3-2
Application
Study and research
Culture Medium
Chocolate agar
Culture Conditions
37°C; Anaerobic
Source
Caecal content; TNFdeltaARE/+ C57BL/6 mouse
Risk Group
2
Genbank Accession Numbers
16S rRNA gene: GQ456205 draft genome; raw reads: ERX1284250
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
Parabacteroides is a Gram-negative, anaerobic, non-spore-forming genus from the family Tannerellaceae. Currently, the genus Parabacteroides includes eight valid species with standing in nomenclature. The species Parabacteroides faecis and Parabacteroides johnsonii; faeces and Parabacteroides gordonii; blood were all isolated for the first time in humans. Of all the species, Parabacteroides distasonis is the reference type strain for the genus Parabacteroides. To date, Parabacteroides distasonis has been shown to have beneficial effects on colorectal cancer. Multiple researchers have identified that levels of Parabacteroides distasonis in stool are inversely correlated to the presence of intestinal tumors. The evidence for the potential anti-inflammatory effects of Parabacteroides distasonis in colorectal cancer is further supported by the inverse correlation between Parabacteroides distasonis levels and IL-1β production in the gut, suggesting that Parabacteroides distasonis has anti-tumorigenic and anti-inflammatory potential in colorectal cancer patients. Further potential benefits of Parabacteroides distasonis have been identified, particularly in relation to obesity. In addition, several studies have suggested that Parabacteroides distasonis may play a role in various forms of autoimmunity.
Alternative Names
Parabacteroides goldsteinii
FAQs Customer Reviews Related Products
What are the main therapeutic applications of Parabacteroides goldsteinii?
Parabacteroides goldsteinii is primarily researched for its potential therapeutic applications in modulating gut microbiota composition. Studies suggest it may influence metabolic health and immune responses.
How is Parabacteroides goldsteinii produced and characterized?
Parabacteroides goldsteinii is produced through rigorous cultivation and purification processes to ensure viability and purity. Characterization includes genomic sequencing and metabolic profiling to validate its identity and properties.
What are the mechanisms by which Parabacteroides goldsteinii exerts its effects?
Parabacteroides goldsteinii is hypothesized to interact with host pathways, influencing inflammatory responses and gut barrier function. These mechanisms are crucial for understanding its potential therapeutic benefits.
How should researchers store Parabacteroides goldsteinii for optimal viability?
Parabacteroides goldsteinii should be stored at ultra-low temperatures (-80°C) to maintain viability and stability. Thawing should be done rapidly to minimize cell stress and ensure functionality in experimental settings.
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