Parabacteroides goldsteinii is a Gram-negative, obligately anaerobic non-spore-forming and non-motile bacterium from the genus of Parabacteroides.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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LBST-045FG |
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Product Information | |
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Product Overview | Parabacteroides goldsteinii is a Gram-negative, obligately anaerobic non-spore-forming and non-motile bacterium from the genus of Parabacteroides. |
Target | Parabacteroides |
Genus | Parabacteroides |
Application | Study and research |
Type Strain | Yes |
Culture Medium | Columbia blood agar |
Culture Conditions | 37°C; Anaerobic |
Risk Group | 2 |
Product Format | Freeze-dried |
Packaging | Ampoule tube |
Storage | -80°C |
Shelf Life | 6 years |
Target Introduction | |
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Introduction | Parabacteroides is a Gram-negative, anaerobic, non-spore-forming genus from the family Tannerellaceae. Currently, the genus Parabacteroides includes eight valid species with standing in nomenclature. The species Parabacteroides faecis and Parabacteroides johnsonii; faeces and Parabacteroides gordonii; blood were all isolated for the first time in humans. Of all the species, Parabacteroides distasonis is the reference type strain for the genus Parabacteroides. To date, Parabacteroides distasonis has been shown to have beneficial effects on colorectal cancer. Multiple researchers have identified that levels of Parabacteroides distasonis in stool are inversely correlated to the presence of intestinal tumors. The evidence for the potential anti-inflammatory effects of Parabacteroides distasonis in colorectal cancer is further supported by the inverse correlation between Parabacteroides distasonis levels and IL-1β production in the gut, suggesting that Parabacteroides distasonis has anti-tumorigenic and anti-inflammatory potential in colorectal cancer patients. Further potential benefits of Parabacteroides distasonis have been identified, particularly in relation to obesity. In addition, several studies have suggested that Parabacteroides distasonis may play a role in various forms of autoimmunity. |
Alternative Names | Parabacteroides goldsteinii; 342457 |
Growth of Parabacteroides goldsteinii is optimal under anaerobic conditions at 37°C, requiring a rich medium supplemented with appropriate growth factors and nutrients.
Parabacteroides goldsteinii has shown potential in modulating gut microbiota composition, enhancing microbial diversity, and possibly influencing host immune responses, which are crucial for maintaining gut homeostasis.
Parabacteroides goldsteinii is stable under recommended storage conditions (-80°C) for long-term preservation, with protocols ensuring viability and functionality upon thawing for experimental use.
Parabacteroides goldsteinii interacts synergistically with certain commensal bacteria, potentially influencing metabolic pathways and contributing to overall gut health through complex microbial interactions.
Studies have demonstrated that Parabacteroides goldsteinii administration in animal models results in beneficial changes in gut microbiota composition, suggesting therapeutic potential in various gastrointestinal conditions, pending further clinical validation.
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For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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