Bifidobacterium bifidum was isolated from human feces. It is is a Gram-positive, anaerobic bacterium that is neither motile nor spore-forming.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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LBST-050FG |
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Product Information | |
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Product Overview | Bifidobacterium bifidum was isolated from human feces. It is is a Gram-positive, anaerobic bacterium that is neither motile nor spore-forming. |
Target | Bifidobacterium |
Genus | Bifidobacterium |
Strain Designation | VIII-210 |
Application | Study and research |
Type Strain | No |
Culture Medium | BBL |
Culture Conditions | 37°C; Anaerobic |
Source | Human feces |
Risk Group | 1 |
Product Format | Freeze-dried |
Packaging | Ampoule tube |
Storage | -80°C |
Shelf Life | 6 years |
Target Introduction | |
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Introduction | Bifidobacterium are Gram-positive, heterofermentative, anaerobic bacteria with a distinctive bifid; i.e. Y shape after which they are named. They are originally isolated from the faeces of breast-fed infants, members of the genus Bifidobacterium are commonly found in the GI tract of mammals. In humans, Bifidobacterium resides within the GI tract, from birth to old age. Disturbances in the microbiota are linked to an ever-growing number of immune-linked disease states including IBD, atopic allergy, arthritis, and obesity. Therefore, there is a significant interest in treating these diseases through microbial or "probiotic" supplementation of patients, including Bifidobacterium. Data from mouse models and clinical trials indicate that Bifidobacterium may have beneficial effects for treating and preventing immune-linked diseases, including gut-associated and systemic conditions. Bifidobacterium have been commercially exploited as probiotic agents due to their associated health benefits and GRAS; Generally Recognised As Safe status. |
Alternative Names | Bifidobacterium bifidum |
Bifidobacterium bifidum thrives best under anaerobic conditions at temperatures ranging from 37 to 40 degrees Celsius. It requires a specialized growth medium enriched with carbohydrates like glucose or lactose for robust cultivation.
Cultures of Bifidobacterium bifidum should be stored at -80 degrees Celsius in a suitable cryoprotective medium, such as glycerol. Regular sub-culturing every 3 to 6 months ensures viability and genetic stability.
Quantification of Bifidobacterium bifidum can be achieved through viable plate counts on selective media like MRS agar, qPCR assays targeting specific genetic markers, or by measuring metabolic activity using spectrophotometry.
Bifidobacterium bifidum is studied for its probiotic properties, including its potential to modulate gut microbiota composition and its effects on immune response regulation. Research also explores its role in gastrointestinal health and its interaction with host cells.
Identity and purity can be confirmed by sequencing specific genomic regions and comparing them against reference sequences. Additionally, biochemical tests and selective growth patterns on differential media can verify the strain's characteristics.
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For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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