Lactobacillus jensenii; 38672 (CAT#: LBST-128FG)

Lactobacillus jensenii; 38672 is commonly used in studies related to the vaginal microbiome, reproductive health, and probiotic development. It has been shown to play a role in maintaining mucosal health by inhibiting pathogens such as Gardnerella vaginalis and Candida albicans. Researchers often investigate its potential as a live biotherapeutic product in preventing bacterial vaginosis and yeast infections.

Lactobacillus jensenii; 38672 requires a specific growth medium for optimal culturing, such as de Man, Rogosa, and Sharpe (MRS) broth or blood agar. The bacteria thrive under anaerobic or microaerophilic conditions, typically at 37°C. Researchers should maintain strict aseptic conditions during culture and use to avoid contamination, especially in long-term studies.

Researchers often study the antimicrobial activities of Lactobacillus jensenii; 38672 by conducting co-culture experiments with pathogenic microorganisms. The bacteria produce lactic acid and other antimicrobial compounds that inhibit the growth of harmful microbes. Assays such as agar diffusion or biofilm inhibition are common methods used to test these effects in vitro.

For long-term storage, Lactobacillus jensenii; 38672 should be kept at -80°C in cryoprotectants such as glycerol (15-20%). Short-term storage can be done at 4°C in a nutrient-rich medium to preserve its viability. Researchers need to periodically verify the viability and purity of the strain to ensure reliable results in experiments.

Lactobacillus jensenii; 38672 can be genetically modified using molecular techniques such as electroporation or transformation with plasmid vectors. Researchers often modify specific genes to explore the strain's functions, such as its role in lactic acid production, adhesion properties, or immune modulation. CRISPR/Cas9-based systems are also increasingly used to target specific gene modifications.