Datasheet

Bacteroides xylanisolvens Chassard et al. 2008

Bacteroides xylanisolvens was isolated from wild mouse. It is a Gram-negative, non-sporulating, rod shaped bacteria.

For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.

Product Information
Product Overview	Bacteroides xylanisolvens was isolated from wild mouse. It is a Gram-negative, non-sporulating, rod shaped bacteria.
Target	Bacteroides
Genus	Bacteroides
Strain Designation	JJM0207_12
Application	Study and research
Type Strain	No
Culture Medium	Medium 339
Culture Conditions	37°C; Anaerobic
Source	Wild mouse
Risk Group	1
Genbank Accession Numbers	16S rRNA gene: KR364742
Product Format	Freeze-dried
Packaging	Ampoule tube
Storage	-80°C
Shelf Life	6 years

Target Introduction
Introduction	Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 3% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.
Alternative Names	Bacteroides xylanisolvens Chassard et al. 2008

Target Introduction

Introduction

Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 3% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.

Alternative Names

Bacteroides xylanisolvens Chassard et al. 2008

FAQs Published Data Customer Reviews Related Products

What are the unique genetic characteristics of Bacteroides xylanisolvens?
The genome of Bacteroides xylanisolvens includes a significant number of elements that may drive phase variation of surface structures, contributing to phage resistance/sensitivity. This includes genes coding for site-specific tyrosine recombinases and DNA invertases, which can affect bacterial adaptability and virulence
How should Bacteroides xylanisolvens be revived from a frozen state for experimental use?
To revive Bacteroides xylanisolvens, thaw the frozen stock rapidly at room temperature and inoculate it into a suitable anaerobic medium that supports its growth. Incubation should be done under strict anaerobic conditions at 37°C to ensure optimal recovery.
What type of medium is recommended for cultivating Bacteroides xylanisolvens?
Bacteroides xylanisolvens grows well in media that can support the fermentation of xylans and other complex polysaccharides. A commonly used medium is one supplemented with xylose as the primary carbon source to promote optimal growth and activity of the bacterium.
Can Bacteroides xylanisolvens be co-cultured with other microbial species?
Yes, Bacteroides xylanisolvens can be co-cultured with other gut microbiota in studies examining interactions within the microbial community. Ensure that the co-culturing conditions are anaerobic and that the media supports the growth of all included species.
How can the metabolic activity of Bacteroides xylanisolvens be quantitatively assessed?
The metabolic activity of Bacteroides xylanisolvens can be assessed by measuring the production of short-chain fatty acids (SCFAs) using gas chromatography. Additionally, pH changes in the culture medium can indicate fermentation activity.

Bacteroides-xylanisolvens-Chassard-et-al-2008-1

Bacterial proteins (a, b) and organic acids (c, d) produced by Bacteroides xylanisolvens XB1AT (a, c) and Roseburia intestinalis XB6B4 (b, d) grown for 6 days at 37°C

The study investigates the specialized xylan degradation capabilities of Bacteroides xylanisolvens, focusing on its role in fiber fermentation in the human gut. By analyzing the bacterium's interaction with various xylan-containing substrates like oat spelt xylan, wheat bran, and vegetable fibers, the research underscores its ability to efficiently break down these complex carbohydrates into short-chain fatty acids (SCFAs), which are vital for colonic health.
The experimental results indicate that Bacteroides xylanisolvens exhibits high xylanase activity, which is crucial for degrading xylans-the predominant polysaccharides in many dietary fibers. The bacterium was particularly effective in fermenting xylan into SCFAs such as acetate and propionate, which have beneficial effects on the intestinal barrier, immune modulation, and overall gut health. This study highlights the bacterium's potential to enhance fiber utilization in the human diet, promoting a healthier gut microbiome and offering implications for dietary recommendations and treatments for digestive disorders.

Mirande, C., Kadlecikova, E., et al. Dietary fibre degradation and fermentation by two xylanolytic bacteria Bacteroides xylanisolvens XB1AT and Roseburia intestinalis XB6B4 from the human intestine. Journal of applied microbiology. 2010, 109(2): 451-460.

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Creative Biolabs' Bacteroides xylanisolvens is essential for our research into metabolic health, offering detailed insights into the role of gut bacteria in metabolism.
Breakthroughs in Gut Health Studies
Using Bacteroides xylanisolvens from Creative Biolabs has led to breakthroughs in our gut health studies, thanks to its superior fermentative capabilities.
Cornerstone in Microbial Ecology
The robust growth and adaptability of Bacteroides xylanisolvens from Creative Biolabs make it a cornerstone for studying complex microbial ecologies.

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For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.