Comprehensive Probiotic Anti-Infection Screening Service (CRO)
Services Applications Advantages FAQs
Comprehensive probiotic anti-infection assay services. From initial screening to detailed mechanism of action studies, Creative Biolabs provides the expertise and platforms you need to thoroughly assess the anti-infective capabilities of your probiotics. Request a Quote
Rapid & Reliable Probiotic Anti-Infection Screening Services for Drug Discovery
Workflow
Probiotic Characterization
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Strict quality control inspections are carried out to ensure: vitality, purity, and stability.
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High-quality probiotic cultures ready for in vitro and in vivo testing.
In Vitro Screening Assays
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Antimicrobial Activity Assays: Test the inhibitory or killing effects of probiotics on the growth of various pathogenic bacteria.
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Agar Diffusion Tests: Assessing the ability of probiotics or their supernatants to inhibit the growth of pathogenic microorganisms on agar plates by measuring zones of inhibition.
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MIC and MBC Assays: Determining the lowest concentration of a probiotic or its antimicrobial substances required to inhibit or kill a specific pathogen in liquid culture.
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Time-Kill Kinetics Studies: Evaluating the rate and extent of pathogen reduction over time when exposed to probiotics or their metabolites.
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Antifungal Activity Assays: Specific tests to determine the inhibitory effects of probiotics against fungal pathogens.
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Anti-Viral Activity: Evaluate the inhibitory effect of probiotics on the growth or infection of viruses.
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Adhesion Assays: Assessment of probiotic adherence to epithelial cells.
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Anti-Biofilm Assays: Measurement of biofilm inhibition or disruption by probiotics.
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Immunomodulatory Assays: Analysis of probiotic effects on host immune responses.
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Anti-Invasion Assays: Determining if probiotics can prevent pathogens from invading host cells.
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Co-aggregation Assays: Assessing the ability of probiotics to aggregate with pathogens, potentially hindering their ability to colonize host surfaces.
In Vivo Efficacy Studies (Animal Models)
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Animal Model Infection Studies: For promising probiotic candidates identified in vitro, we conduct in vivo efficacy studies using relevant animal models of infection. These studies assess the ability of probiotics to prevent or treat infections, reduce pathogen load, and improve host health.
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Impact on Host Immune Response: Assessing the probiotic's ability to modulate the immune system to fight infection.
Data Analysis and Reporting
Our team of expert scientists and bioinformaticians performs rigorous data analysis using appropriate statistical methods. We provide comprehensive reports summarizing the study findings, including detailed methodologies, results, and interpretations.
Deliverables
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Deliverable Components
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Details
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Comprehensive Study Report
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Detailing the experimental design, methodologies, results, and conclusions.
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Raw and Processed Data Files
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Microbiological Assay Data
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Analyzed Data and Statistical Reports
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Turnaround Time
The typical timeframe for this service ranges from 8 to 16 weeks, depending on the complexity of the study design, the number of probiotic strains and pathogens evaluated, and the specific in vivo models used.
Applications
Pharmaceutical and Biotechnology Research & Development
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Identifying Novel Anti-Infective Agents.
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Developing Probiotic-Based Therapeutics.
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Combating Antibiotic Resistance.
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Vaccine Enhancement.
Functional Foods and Nutraceuticals
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Developing Probiotic-Enriched Products.
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Validating Health Claims.
Animal Health and Agriculture
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Developing Probiotic Feed Additives.
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Improving Animal Health and Productivity.
Personal Care and Cosmetics
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Developing Anti-Microbial Formulations.
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Maintaining Skin Microbiome Balance.
Basic Research and Academia
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Understanding Host-Microbe Interactions.
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Elucidating Mechanisms of Action.
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Exploring Novel Applications.
Advantages
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Comprehensive Screening Platform
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Customized Study Design
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Rigorous Quality Control
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Expert Scientific Team
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Fast Turnaround Times
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Data-Driven Insights
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Established Methodological Framework
Unlocking the anti-infective secrets of your probiotics is within reach. Creative Biolabs' comprehensive screening services provide the robust insights you're looking for. Do you have specific questions about our assays or how we can support your research? We're here to help! Drop us a line or give us a call – we're always happy to discuss your project and find the best path forward.
FAQs
What exactly do you test for?
We see if your probiotics can fight off harmful microbes like bacteria and viruses. Our tests show how well they inhibit or kill these bad bugs.
What kinds of tests do you run?
We've got lab tests in dishes and ways to mimic living systems. This helps us understand how your probiotics work in different scenarios.
Can you test my specific probiotic strains?
Yes, that's what we're here for! Just send them our way, and we'll get to work evaluating their potential.
What kind of results will I see?
You'll get clear data showing how effective your probiotics are against specific infections. Think numbers and easy-to-understand reports.
Is the data you provide reliable?
Absolutely. We stick to good science and quality control to make sure our results are accurate and you can trust them.
Can you help me figure out the best tests for my needs?
For sure! Let's chat about what you're hoping to learn, and we can design a smart testing plan together.
What's a general idea of the cost?
It varies depending on the number of probiotics and tests, so it's best to get in touch for a specific quote. We'll make sure it's clear and upfront.
Customer Reviews
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"Using Creative Biolabs' Probiotic Anti-Infection Screening Services in our research has significantly improved our ability to identify probiotic strains with strong anti-inflammatory effects in a mouse model of colitis." J**n Smith.
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"The comprehensive in vitro assays provided by Creative Biolabs have greatly facilitated our understanding of the mechanisms by which our probiotic candidate inhibits pathogen adhesion and biofilm formation." M**a Garcia.
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"Creative Biolabs' in vivo efficacy studies provided robust and reliable data that was crucial for advancing our probiotic-based therapy into clinical trials. The detailed reports and expert consultation were invaluable." D**d Lee.
For Research Use Only. Not intended for use in
food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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