Live Biotherapeutics Products cGMP Manufacturing
Live biotherapeutic products (LBPs), a revolutionary new class of medicines for which the active substance is a living microorganism, are currently being developed for multiple indications. Based on years of industry experience in drug discovery, Creative Biolabs has expanded its expertise in microbiota and microbiome science and developed a Live Biotherapeutics platform for discovery, product development, pre-clinical studies, and cGMP manufacturing of LBPs.
LBPs cGMP Manufacturing
We offer a full-service operation of LBPs manufacturing in compliance with GMP standards. Our diverse products can address different demands for new therapeutic possibilities on the horizon, including the therapy of lung and oral infections as well as metabolic diseases and cancers.
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Manufacturing Capabilities
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Strains
We have an extensive library of proprietary human bacterial strains that can be developed as LBPs, including aerobic and anaerobic organisms. The list is just a small part of our portfolio.
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Equipment
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Biological safety cabinets
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Anaerobic work stations with internal HEPA filtration (fermentation tank)
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Bioreactors (20 liters, 300 liters, 3,500 liters, etc.)
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Closed harvest systems
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Lyophilizers
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Separation and filling equipment
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QC/QA Assays
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PCR
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High-performance Liquid Chromatography (HPLC)
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Spectrophotometers
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Plate readers fluorescent and UV
LBPs represents a revolutionary approach to the prevention and treatment of human disease. Creative Biolabs has abundant experience in working with many different types of LBPs to help our customers to create a robust and controlled process, accelerating products through the various clinical phases towards commercial launch. If you are interested in our services, please feel free to contact us.
Reference
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Bermúdez-Humarán, L. G.; Langella, P. Live bacterial biotherapeutics in the clinic. Nature biotechnology. 2018, 36(9): 816-818.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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