Bacillus coagulans GBI-30 6086 is a beneficial spore-forming, lactic acid-producing bacteria (probiotic).
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information
Product Overview
Bacillus coagulans GBI-30 6086 is a beneficial spore-forming, lactic acid-producing bacteria (probiotic).
Target
Bacillus
Genus
Bacillus
Application
Study and research
Type Strain
Yes
Culture Medium
Nutrient Agar
Culture Conditions
37°C, Facultative anaerobic
Risk Group
1
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
Bacillus is a genus of Gram-positive, rod-shaped bacteria, a member of the phylum Bacillota. Bacillus species can be either obligate aerobes which are dependent on oxygen, or facultative anaerobes which can survive in the absence of oxygen.
Alternative Names
B. coagulans
FAQsPublished Data Customer Reviews Related Products
What are the key parameters to monitor during a study using Bacillus coagulans ?
Key parameters include the viability of the spores, gastrointestinal symptoms, immune response markers, and overall health outcomes such as digestive and protein absorption metrics.
What are the stability considerations for Bacillus coagulans in different formulations?
Bacillus coagulans is highly stable in various formulations including capsules, powders, and functional foods. It remains viable through manufacturing processes and shelf life, making it versatile for research and product development.
What is the recommended dosage for Bacillus coagulans in research?
The recommended dosage varies depending on the specific research protocol. Commonly, doses range from 1 to 5 billion CFUs per day, administered in single or divided doses.
How can Bacillus coagulans be incorporated into food products for research?
Bacillus coagulans can be incorporated into various food products, such as yogurt, juice, and baked goods. The spores can withstand heat and acidic conditions, making them suitable for diverse food matrices. Proper mixing and processing conditions should be maintained to ensure even distribution.
What are the main health benefits observed from using Bacillus coagulans in research?
Research has shown that Bacillus coagulans supports digestive health, enhances protein absorption, and boosts immune function. These benefits have been observed in various clinical and pre-clinical studies, highlighting its efficacy in promoting overall health.
Mouse survival data
The research investigated the effects of Bacillus coagulans GBI-30, 6086 (BC30) on C. difficile-induced colitis in mice. Female C57BL/6 mice were administered either a vehicle or BC30 (2 × 10^9 CFU per day) for 15 days. Mice infected with C. difficile showed significant improvement in survival rates and stool consistency when treated with BC30. On study day 12, 67% of the BC30-treated mice had normal stools compared to only 13% in the vehicle-treated group (p = 0.0002). By day 16, 24% of BC30-treated mice still had normal stools versus 0% in the vehicle group (p = 0.0187). Additionally, BC30 treatment significantly reduced the stool consistency score (1.1 ± 0.2) compared to the vehicle group (1.9 ± 0.2). The BC30-treated mice also exhibited attenuated colonic pathology and reduced levels of colonic MIP-2 chemokine, indicating anti-inflammatory effects. The findings suggest that BC30 can effectively mitigate symptoms of C. difficile-induced colitis, improving gut health and reducing inflammation.
Fitzpatrick, L. R., Small, J. S., et al. Bacillus coagulans GBI-30 (BC30) improves indices of Clostridium difficile-induced colitis in mice. Gut pathogens. 2011, 3: 1-9. Distributed under Open Access license CC BY 4.0, without modification.
Remarkable Stability Bacillus coagulans from Creative Biolabs exhibited remarkable stability in our heat-stress experiments, outperforming similar products. This strain is essential for robust probiotic formulation development.
Enhanced Efficacy
In our gastrointestinal model studies, Bacillus coagulans demonstrated enhanced efficacy in maintaining viability and functionality, providing significant advantages over competitor strains.
Superior Shelf-Life
The superior shelf-life of Bacillus coagulans is impressive, making it an ideal choice for long-term research projects. Creative Biolabs has outdone itself with this high-quality product.
Exceptional Probiotic Characteristics
The exceptional probiotic characteristics of Bacillus coagulans have proven invaluable in our research on gut microbiota modulation. This strain surpasses similar offerings from other suppliers.
Robust Performance
The robust performance of Bacillus coagulans in stress tolerance assays is commendable. Creative Biolabs offers a top-tier product that significantly aids in advancing drug research and development.
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