Alistipes is a relatively new genus of bacteria isolated primarily from medical clinical samples, although at a low rate compared to other genus members of the Bacteroidetes phylum, which are highly relevant in dysbiosis and disease.
Alternative Names
Alistipes finegoldii
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What are the optimal growth conditions for Alistipes finegoldii?
Alistipes finegoldii thrives under strict anaerobic conditions at 37°C. It requires a complex medium, such as PYG (peptone yeast glucose) supplemented with vitamins. Growth can be challenging in liquid media, often requiring specific supplementation for optimal yield. This species shows resistance to bile and certain antibiotics like vancomycin, aiding in its survival in gut-related environments.
How is Alistipes finegoldii used in the development of probiotics?
In probiotic research, Alistipes finegoldii is studied for its ability to influence gut microbial communities and support overall gut homeostasis. Its resistance to bile and capacity to ferment amino acids allow it to thrive in the gut, making it a strong candidate for developing next-generation probiotics that could treat gut-related disorders and improve immune function.
What challenges might arise during the isolation of Alistipes finegoldii from samples?
Due to its strict anaerobic nature, isolating Alistipes finegoldii from clinical or environmental samples requires careful sample handling in anaerobic chambers. In addition, the strain's slow growth in liquid media may prolong the isolation process. Controlling contamination and ensuring optimal culture conditions are essential for successful isolation.
What molecular techniques are used to study Alistipes finegoldii?
Molecular techniques like 16S rRNA sequencing are commonly employed to identify and characterize Alistipes finegoldii. Whole-genome sequencing has also provided insights into its genetic composition and metabolic pathways. Researchers utilize these methods to study its interactions within the gut microbiome and its role in disease progression.
How does Alistipes finegoldii interact with other gut microbiota in human health studies?
Alistipes finegoldii has been observed to play a key role in maintaining microbial diversity in the gut. It interacts with other commensal bacteria to modulate immune responses and maintain gut barrier integrity. Research is ongoing to explore its synergistic effects with other probiotic strains, which could enhance its efficacy in treating conditions like metabolic disorders and chronic inflammation.
Superior for Gut Microbiota Research Alistipes finegoldii from Creative Biolabs has been instrumental in our gut microbiota research. Its high-quality strain allowed us to achieve precise insights, outperforming similar products from competitors.
Exceptional Performance in Metabolomics Studies
We used this Alistipes finegoldii strain in metabolomics studies, and it offered superior reproducibility. Creative Biolabs' product stands out for its consistency compared to other suppliers.
Key Role in Inflammation Research
Creative Biolabs' Alistipes finegoldii was essential in our inflammation studies. Its purity and quality made it a superior choice for in vitro experiments, delivering outstanding results.
Valuable for Host-Microbe Interaction Studies
We found Creative Biolabs' Alistipes finegoldii to be the best choice for studying host-microbe interactions. Its reliability and quality exceeded other brands we've tried, accelerating our drug development process.
Highly Effective in Immune Modulation
Creative Biolabs' Alistipes finegoldii was critical for our immune modulation studies. The strain's quality allowed us to achieve more accurate and reliable data.
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