Akkermansia muciniphila was isolated from human feces. It is a species of human intestinal mucin-degrading bacterium. It is a Gram-negative, strictly anaerobic, non-motile, non-spore-forming, oval-shaped bacterium.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
CAT
Size
Price
Quantity
LBST-010FG
Product Information
Product Overview
Akkermansia muciniphila was isolated from human feces. It is a species of human intestinal mucin-degrading bacterium. It is a Gram-negative, strictly anaerobic, non-motile, non-spore-forming, oval-shaped bacterium.
Target
Akkermansia
Genus
Akkermansia
Strain Designation
Muc
Application
Study and research
Type Strain
Yes
Culture Medium
Chocolate agar/BHI
Culture Conditions
37°C; Anaerobic
Source
Human feces
Characteristics
Gram-negative bacteria, strictly anaerobic, non-motility, non-spore-producing elliptic bacteria that grow singly, in pairs, and in clumps in media containing mucins.
Risk Group
1
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
Akkermansia is a genus in the phylum Verrucomicrobia; Bacteria with the type species Akkermansia muciniphila. Among the next-generation beneficial microbes that have been identified, Akkermansia muciniphila is a promising candidate. Akkermansia muciniphila is a strict anaerobe recently isolated from human faeces and uses the mucin as the sole sources of carbon and nitrogen elements. Due to this unique function and its high universality and richness in almost all life stages, Akkermansia muciniphila opened new avenues for the application in next-generation therapeutic probiotic. It is a bacterium of oval shape, non-motile and Gram-negative and forms no endospores and widely distributed in the intestines of human and animals. Akkermansia muciniphila is one of the normal gut symbionts throughout our life. Currently, a large number of researches on Akkermansia muciniphila mainly focused on explaining its relationship with diseases. It promises to be a therapeutic target in the microbiota-related diseases, such as colitis, metabolic syndrome, immune diseases and cancer. Preliminary human data suggest oral administration of Akkermansia muciniphila safe, but its effect needs to be further verified in more human clinical trials in the near future.
Alternative Names
Akkermansia muciniphila; Muc
FAQsPublished Data Customer Reviews Related Products
How is Akkermansia muciniphila supplied?
It is provided in a lyophilized form, ensuring stability and ease of transport.
Are there any storage requirements for the product?
Yes, it should be stored at -80°C for optimal viability and longevity.
How can researchers ensure the authenticity of the strains?
Each batch undergoes rigorous quality control and genomic sequencing for verification.
Can Akkermansia muciniphila be used in clinical?
No, this product is strictly for research purposes and not for diagnostic or therapeutic use.
Akkermansia muciniphila administration reduced C. difficile-induced colon damage
The study depicts the positive impact of Akkermansia muciniphila on colon damage induced by Clostridioides difficile. The figure includes a comprehensive experimental plan and the survival rates of mice, which improved with A. muciniphila administration. It also shows the body weight and diarrhea scores, which indicate better health outcomes in the presence of A. muciniphila. The length of the colon, which is a marker of colonic health, was maintained in the treated group. Additionally, the load of C. difficile in feces and the levels of toxins A and B were significantly reduced in the group treated with A. muciniphila, highlighting its therapeutic potential in mitigating C. difficile infection.
Wu, Z., et al. Akkermansia muciniphila Ameliorates Clostridioides difficile infection in mice by modulating the intestinal microbiome and metabolites. Frontiers in microbiology. 2022, 13: 841920. Distributed under Open Access license CC BY 4.0, without modification.
Gastrointestinal Genius
Transforms gastrointestinal research with its exceptional performance in symbiotic interactions studies.
Leading Probiotic Research
This product excels in probiotic research, offering distinct advantages in gastrointestinal studies, enhancing data fidelity and accelerating scientific inquiry.
Metabolic Research Milestone
Essential for metabolic research, the Akkermansia muciniphila; Muc product provides unparalleled insights into host-microbe interactions, aiding in groundbreaking discoveries.
Catalyst for Discovery
The Akkermansia muciniphila; Muc provided by Creative Biolabs is the cornerstone for probiotic research, outshining its counterparts.
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