Lab-scale Production of Healthy Fecal Microbiota Suspension Service
Services Deliverables Applications Advantages FAQs
Creative Biolabs offers standardized, lab-scale production of healthy fecal microbiota suspensions, ensuring high microbial viability and consistency for reproducible microbiome research. We provide suspensions from rigorously screened donors, suitable for preclinical studies, assay development, and related applications.Request a quote
Advanced Fecal Microbiota Solutions
Workflow
Services Details
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Donor Selection and Characterization (Animal Specific)
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Species-Specific Donors (e.g., mice, rats, pigs): Donors are typically from specific pathogen-free (SPF) or germ-free colonies, depending on the study's requirements.
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Microbiota Profiling: Extensive characterization of the donor's fecal microbiota is performed using techniques like 16S rRNA sequencing or metagenomics.
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Fecal Microbiota Processing (Animal Focused)
1. Standardized Collection
2. Processing steps (dilution, filtration, homogenization) are standardized to minimize variability. Anaerobic conditions are often maintained to preserve the viability of anaerobic bacteria.
3. Quality Control (Animal Relevant)
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Microbiological testing to ensure the suspension is free from relevant animal pathogens.
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Compositional analysis is conducted to confirm the desired microbial profile.
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Viability assays are performed to confirm the amount of live bacteria in the suspension.
4. Cryopreservation and Storage
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Cryopreserved using appropriate cryoprotectants.
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Storage is at ultra-low temperatures to ensure long-term stability.
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Additional service
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Customized Suspension Preparation: Services may offer customized suspensions based on specific experimental requirements (e.g., specific bacterial groups, defined diversity).
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Data Analysis Assistance: Some services may offer assistance with analyzing microbiota data generated from the animal studies.
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Estimated Timeframe
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Project timelines typically range from 4 to 8 weeks, contingent on donor availability, processing complexity, and QC stringency.
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Deliverables
The final deliverable is a well-characterized, viable, and standardized fecal microbiota suspension, accompanied by comprehensive documentation, delivered in a format suitable for animal administration.
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Items
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Contents
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The Fecal Microbiota Suspension Product
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It's a liquid or frozen suspension containing a defined community of microorganisms sourced from healthy animal donors.
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The suspension will be provided in a format that allows for easy and reliable administration to the animals, whether via oral gavage, enema, or other appropriate routes.
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Certificate of Analysis
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A detailed report containing the results of all quality control tests, including data on microbial viability, composition (e.g., relative abundance of key bacterial taxa), and safety (e.g., absence of pathogens).
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Storage and Handling Instructions
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Comprehensive guidelines for the proper storage, thawing, and handling of the fecal microbiota suspension to ensure optimal results in downstream applications.
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Applications
1. Gut Microbiota Research
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Understanding the role of the gut microbiota in animal health and disease.
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Exploring the mechanisms by which the gut microbiota influences host physiology.
2. Disease Modeling and Therapeutics
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Developing animal models of human and animal diseases related to gut dysbiosis.
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Evaluating the efficacy of fecal microbiota transplantation (FMT) and other microbiome-targeted therapies.
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Studying the impact of FMT on various conditions, including inflammatory bowel disease (IBD), metabolic disorders, and neurological diseases.
3. Drug Development
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Assessing the effects of new drugs on the gut microbiota.
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Investigating the potential of microbiome-based therapeutics.
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Evaluating the impact of drug delivery methods on microbiome composition.
4. Nutrition and Feed Studies
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Evaluating the impact of different feed formulations on animal gut health and performance.
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Developing prebiotics and probiotics to improve animal gut health.
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Studying the impact of the microbiome in livestock production.
5. Immunology and Infectious Disease
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Investigating the role of the gut microbiota in immune system development and function.
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Studying the impact of the gut microbiota on susceptibility to infectious diseases.
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Studying the impact of the microbiome on vaccine efficacy.
6. Toxicology
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Studying the impact of toxicants upon the gut microbiome.
Why Us?
High-Quality Starting Material
We use fecal samples from carefully screened healthy donors, ensuring a rich and diverse microbial community.
Optimized Processing Protocols
Microbial viability and diversity are preserved through validated protocols, critical for downstream assays. Creative Biolabs' methodology reflects current research on stool processing and its impact on microbiota composition.
Stringent Quality Control
Product safety and consistency are ensured via microbial viability assays and molecular profiling.
Customizable Solutions
We offer flexible service options and can tailor our protocols to meet specific client requirements, including donor selection criteria and processing parameters.
Reliable supply
Creative Biolabs offers a standardized and reliable source of fecal microbiota suspensions.
Creative Biolabs aims to supply robust, customizable fecal microbiota suspensions for your research. We prioritize quality and collaborative design.
Contact Our Team to discuss your project-specific needs.
FAQs
What methods are used to characterize the microbiota?
Aerobic/anaerobic culture, 16S/metagenomic profiling, viability assays to analyze the microbial composition of the suspensions.
How is the viability of the microbiota assessed?
We use, e.g., CFU counting, and flow cytometry, to assess the viability of the bacteria in the suspension.
What administration methods are recommended?
Administration, via gavage or enema, requires species-specific considerations. We can advise on tailored approaches.
Can you generate microbiota suspensions with specific compositions?
We provide custom microbiota suspensions, designed around specific bacterial groups or diversity profiles. Let's discuss your experimental needs.
Customer Reviews
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"Using Creative Biolabs' Fecal Microbiota Suspension in our research has significantly improved the consistency and reliability of our in vitro assays." [09/2023], J**e Smith
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"Creative Biolabs' Fecal Microbiota Suspension provided a robust and well-characterized starting material for our animal model studies, accelerating our research on gut microbiome interactions." [05/2024] M**k Brown
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"The detailed Certificate of Analysis and the consistent quality of Creative Biolabs' Fecal Microbiota Suspension have greatly facilitated our drug discovery efforts." [01/2025] S**a Williams
For Research Use Only. Not intended for use in
food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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