Bacteriophage Detection for Live Biotherapeutic Products
Overview Services FAQs
Creative Biolabs provides one of the world's most expert testing services to detect phage for live biotherapeutic products that fulfill the criteria of being rapid, simple, and inexpensive. Our scientists have the skills and abilities deriving from specialist knowledge to meet our customers' specific demands.
Overview
Bacteriophages (phages) are viruses that specifically infect host bacterial species or strains. Phage contamination of microbial cultures is a common complication for the biotech and pharmaceutical industries to produce live biotherapeutic products. The presence of phages, due to difficult detection, increases the risk of false-negative bacteriophage test results that can have disastrous consequences for biological production facilities, destroying the bacterial culture and prolonged contamination of the facility. Monitoring of phages responsible for the failure of microbe-based industrial processes such as live biotherapeutic products requires some fast, inexpensive, and sensitive methods for routine monitoring products.
Bacteriophage Detection Services at Creative Biolabs
Quick and sensitive detection of bacteriophages is important during biotechnological and biopharmaceutical processes to determine the infections with bacteriophages for live biotherapeutic products. Our scientists have extensive experience in phage work. Meanwhile, our service is a one-stop solution for phage testing, detection, removal, and inactivation to ensure your samples are free of phage contamination. For phage detection of live biotherapeutic products, we always use an array of strains optimized for your samples. Such a personalized approach guarantees that we will not miss a phage present in any sample sent to us, regardless of the nature of the samples. When you send us your samples for bacteriophage detection, you can be sure that they are in good hands. Our available methods for phage detection and quantification include culture-dependent detection, sequence-based detection, and particle-based detection. We will visit the idea of the most suitable method for the detection and quantification of bacteriophages in specific kinds of samples at high levels of sensitivity. And, all our tests come at competitive pricing and with short timelines.
Methods
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Double agar layer (DAL) method
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Direct detection of viral particles by PCR
Samples
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Bacterial cultures
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Cell bank
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Others
Turnaround Time
From 4-6 weeks.
Deliverables
Upon completion of the testing services, a final report will be issued.
Frequently Asked Questions
What are the applications of Bacteriophage contamination detection?
Bacteriophage contamination detection has several valuable applications:
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Pathogen Detection
Bacteriophages specifically target and infect bacteria. Using phages for pathogen detection allows rapid and accurate identification of bacterial targets.
Phage-based biosensors are utilized for developing low-cost lab-on-chip (LOC) and point-of-care (POC) devices.
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Biocontrol in Food and Environment
Bacteriophages can be directly applied to foods and food-related environments as biocontrol agents.
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Quality Control in Biotech and Pharmaceutical Industries
Phage contamination of bacterial cultures is common in biotech and pharmaceutical industries. Detecting phage presence is crucial because it can interfere with bacterial identification and isolation.
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Targeted Removal of Specific Pathogens
Bacteriophages with high host-specificity can be applied for the targeted removal of specific pathogens.
What samples need bacteriophage testing?
Bacteriophage testing is relevant for various sample types, including:
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Food and Beverages
Testing food products for bacterial contamination.
Ensuring safety and quality.
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Water
Monitoring drinking water, wastewater, and recreational water bodies.
Assessing water treatment effectiveness.
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Biotech and Pharma Labs:
Verifying bacterial culture purity.
Detecting phage contamination in fermentations.
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Clinical Diagnostics
Identifying bacterial infections.
Monitoring treatment progress.
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Environmental Studies
Investigating microbial communities in soil, sediments, and aquatic ecosystems.
Studying phage-host interactions.
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Veterinary Medicine
Detecting bacterial infections in animals.
Assessing phage presence in animal microbiomes.
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Bioremediation and Agriculture
Evaluating phage impact on soil health and plant growth.
Using phages for biocontrol.
Bacteriophage testing provides insights into bacterial populations and contamination risks.
Creative Biolabs offers more effective detection and better performance in phage detection, resulting from an individual approach to customer samples, along with abilities to work on virtually any culturable bacterial species for live biotherapeutic products. We are dedicated to timely, high-quality service from the start of your project to the finish. Contact us to discuss how we can support you in your project.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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