Enterococcus durans is a microaerophile, mesophilic bacterium that was isolated from excrement of weaned piglets.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information | |
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Product Overview | Enterococcus durans is a microaerophile, mesophilic bacterium that was isolated from excrement of weaned piglets. |
Target | Enterococcus |
Genus | Enterococcus |
Strain Designation | 4ADU-4 |
Application | Study and research |
Type Strain | No |
Culture Medium | BHI |
Culture Conditions | 37°C; Facultative anaerobic |
Source | Excrement of weaned piglets |
Risk Group | 1 |
Product Format | Freeze-dried |
Packaging | Ampoule tube |
Storage | -80°C |
Shelf Life | 6 years |
Target Introduction | |
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Introduction | Enterococcus are lactic acid bacteria; LAB comprising both pathogenic and commensal microorganisms ubiquitous in environment even as gut symbionts. They are extensively studied as potential candidate probiotics. Several number of Enterococcus strains have been reported to produce antimicrobial compounds including bacteriocins. Bacteriocin production have be applied to preservation of a wide range of food products and is now being considered as a probiotic trait. Besides, bacteriocins are considered as promising alternative to fight emerging antimicrobial resistance. Enterococcus probiotics can be used in treatment and/or prevention of certain human and animal diseases such as alleviation of irritable bowel syndrome symptoms and antibiotic-induced diarrhea and prevention of different functional and chronic intestinal diseases. Moreover, some Enterococcus exhibit anticarcinogenic, hypocholesterolemic, as well as immune regulation effects. |
Alternative Names | Enterococcus durans |
Enterococcus durans; 4ADU-4 is primarily used in probiotic research to study its effects on gastrointestinal health, immune modulation, and pathogen inhibition. Its ability to adhere to intestinal mucosa and produce antimicrobial substances makes it a valuable candidate for probiotic development.
Genetic modification of Enterococcus durans; 4ADU-4 can be performed using CRISPR-Cas9 systems, plasmid vectors, and electroporation techniques. These tools enable the study of gene function and enhance its probiotic properties, such as increased adhesion and antimicrobial production.
Safety assessments for Enterococcus durans; 4ADU-4 include genomic analysis to ensure the absence of virulence factors, antibiotic resistance testing, and in vitro assays to confirm its non-pathogenic nature. These steps are crucial to validate its safety for human use.
The antimicrobial activity of Enterococcus durans; 4ADU-4 is evaluated using agar well diffusion, disk diffusion, and broth microdilution assays. These methods measure its effectiveness against various pathogenic bacteria, highlighting its potential as a probiotic with antimicrobial properties.
Enterococcus durans; 4ADU-4 cultures should be stored at -80°C with cryoprotectants like glycerol to maintain long-term viability. For short-term storage, refrigeration at 4°C on solid media is adequate. Regular viability assessments are crucial to ensure culture integrity.
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For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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