Akkermansia muciniphila was isolated from human feces. It is a species of human intestinal mucin-degrading bacterium. It is a Gram-negative, strictly anaerobic, non-motile, non-spore-forming, oval-shaped bacterium.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
CAT
Size
Price
Quantity
LBST-012FG
Product Information
Product Overview
Akkermansia muciniphila was isolated from human feces. It is a species of human intestinal mucin-degrading bacterium. It is a Gram-negative, strictly anaerobic, non-motile, non-spore-forming, oval-shaped bacterium.
Target
Akkermansia
Genus
Akkermansia
Application
Study and research
Type Strain
Yes
Culture Medium
Thioglycolate medium
Culture Conditions
37°C; Anaerobic
Source
Human feces
Risk Group
1
Product Format
Freeze-dried
Packaging
Ampoule tube
Storage
-80°C
Shelf Life
6 years
Target Introduction
Introduction
Akkermansia is a genus in the phylum Verrucomicrobia; Bacteria with the type species Akkermansia muciniphila. Among the next-generation beneficial microbes that have been identified, Akkermansia muciniphila is a promising candidate. Akkermansia muciniphila is a strict anaerobe recently isolated from human faeces and uses the mucin as thesole sources of carbon and nitrogen elements. Due to this unique function and its high universality and richness in almost all life stages, Akkermansia muciniphila opened new avenues for the application in next-generation therapeutic probiotic. It is a bacterium of oval shape, non-motile and Gram-negative andforms no endospores and widely distributed in the intestines of human and animals. Akkermansia muciniphila is one of the normal gutsymbionts throughout our life. Currently, a large number of researches on Akkermansia muciniphila mainly focused on explaining its relationship with diseases. It promises to be a therapeutic target in the microbiota-related diseases, such as colitis, metabolic syndrome, immune diseases and cancer. Preliminary human datasuggest oral administration of Akkermansia muciniphila safe, butits effect needs to be further verified in more human clinical trials in the near future.
Alternative Names
Akkermansia muciniphila Derrien et al.
FAQs Customer Reviews Related Products
What are the optimal storage conditions for Akkermansia muciniphila Derrien et al.?
Akkermansia muciniphila Derrien et al. should be stored at -80°C to maintain its viability and integrity. It is crucial to avoid repeated freeze-thaw cycles to prevent degradation and ensure consistent results in research applications.
What are the recommended growth conditions for Akkermansia muciniphila Derrien et al.?
Akkermansia muciniphila Derrien et al. requires anaerobic conditions for optimal growth. Researchers should use a suitable anaerobic chamber or system to maintain an oxygen-free environment. The ideal temperature for culturing is 37°C, with a growth medium that supports mucin degradation.
How can Akkermansia muciniphila Derrien et al. be quantified in a sample?
Akkermansia muciniphila Derrien et al. can be quantified using quantitative PCR (qPCR) targeting specific genetic markers unique to the strain. Additionally, flow cytometry and colony-forming unit (CFU) counting on selective agar plates are effective methods for quantification.
What are the common applications of Akkermansia muciniphila Derrien et al. in research?
Akkermansia muciniphila Derrien et al. is widely used in studies related to gut microbiota, metabolic disorders, and immune system modulation. It serves as a model organism for understanding mucin degradation and its impact on gut health, obesity, and diabetes.
How can the viability of Akkermansia muciniphila Derrien et al. be assessed?
The viability of Akkermansia muciniphila Derrien et al. can be assessed using live/dead staining techniques combined with fluorescence microscopy or flow cytometry. Additionally, plating on selective media and monitoring colony formation provides an indication of viable bacterial counts.
Exceptional Growth Consistency
The Akkermansia muciniphila Derrien et al. product from Creative Biolabs consistently delivers robust growth under anaerobic conditions. This reliability has significantly enhanced our gut microbiota research.
Superior Viability
Creative Biolabs' Akkermansia muciniphila Derrien et al. exhibits outstanding viability, even after extended storage. This stability is crucial for our long-term metabolic disorder studies.
Excellent Quantification Accuracy
Using Creative Biolabs' Akkermansia muciniphila Derrien et al., accurate quantification through qPCR has been seamless, making our microbiota analyses more precise and dependable.
High-Quality Culturing Akkermansia muciniphila Derrien et al. from Creative Biolabs offers high-quality culturing with minimal contamination, making it ideal for our immune system modulation studies.
Reliable Mucin Degradation
This strain's effective mucin degradation has been pivotal in understanding gut health dynamics. Its application has accelerated our research into gut barrier functions.
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