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Lactococcus lactis

Lactococcus lactis has been identified as an efficient Gram-positive cell factory for the production of recombinant protein. The advantages of this system have led to the use of lactococci in several fields of biotechnology, e.g., the expression of bacterial and viral antigens for safe vaccination via mucosal immunization, the production of human cytokines and other therapeutic agents for in situ treatments, the use of lactococci as a cell factory for the production of specific compounds, and the pilot production of pharmaceutical products.

Genetically Modified Probiotics

CAT#	Product Name	Product Overview	Add to basket
LBGF-0126-GF51	Lactococcus lactis-mBD14	This is an antimicrobial-secreting strain engineered to produce mouse Beta-Defensin 14 (mBD14). It is designed to bolster the host's innate immune defense against enteric pathogens.	Inquiry
LBGF-0126-GF52	Lactococcus lactis-TyrL	This strain is engineered to act as a living metabolic factory for the production of L-DOPA or related catecholamines via tyrosine modification. It is often investigated for its potential to deliver neuroactive compounds to the gut-brain axis.	Inquiry
LBGF-0126-GF54	Lactococcus lactis-elafin	This strain is engineered to secrete Elafin, a powerful protease inhibitor naturally found in the human gut but often deficient in IBD patients. It acts to neutralize excessive inflammatory enzymes that damage the intestinal wall.	Inquiry
LBGF-0126-GF57	Lactococcus lactis-GFP	The industry-standard fluorescent strain for the food-grade bacterium L. lactis. It is the most common model used to validate the survival of "living pills" during their journey through the stomach.	Inquiry
LBGF-0126-GF60	Lactococcus lactis-endostatin	This strain is engineered for anti-angiogenic cancer therapy. They secrete Endostatin, a protein that prevents tumors from forming the new blood vessels they need to grow and spread.	Inquiry
LBGF-0126-GF59	Lactococcus lactis-hADH1B	This "hangover-relief" strain is engineered to express high levels of human Alcohol Dehydrogenase 1B (hADH1B). It is designed to degrade alcohol (ethanol) directly in the gastrointestinal tract before it enters the bloodstream.	Inquiry

For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.