Helicobacter is a genus of Gram-negative bacteria with a characteristic spiral shape. H. pylori is a significant human pathogen that colonizes the stomach and is a major cause of gastritis, peptic ulcers, and gastric cancer. Genomic DNA from Helicobacter is crucial for studying its unique adaptation to the acidic stomach environment and its role in disease. It is used for developing diagnostic tests and new treatments for gastric infections.