Christensenella is a Gram-negative, strictly anaerobic genus of bacteria first discovered in the human gut. Christensenella massiliensis was isolated from human stool specimen from a 66-year-old patient.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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Christensenella is a Gram-negative, strictly anaerobic genus of bacteria first discovered in the human gut. Christensenella massiliensis was isolated from human stool specimen from a 66-year-old patient.
Christensenella is a Gram-negative, non-spore-forming, anaerobic, and nonmotile genus from the family Christensenellaceae. Christensenella minuta, Christensenella timonensis, and Christensenella massiliensis are currently the only known species of Christensenella, all of which were isolated from human stool samples. Development of therapeutic applications for Christensenella is an area of active research. Bacteria of the Christensenellaceae family hold great potential for therapeutic use as live biotherapeutic products to treat obesity and associated metabolic disorders. The larger role of Christensenella in the gut microbiome has also been a focal point for understanding how it may relate to other diseases.
Alternative Names
Christensenella timonensis
FAQs Customer Reviews Related Products
What are the recommended culture conditions for Christensenella timonensis in laboratory settings?
Christensenella timonensis thrives under anaerobic conditions at 37°C, requiring a growth medium enriched with specific substrates like xylose and peptone to support optimal growth and metabolism.
How can Christensenella timonensis be preserved for long-term viability?
To maintain viability, Christensenella timonensis cultures should be stored at -80°C in a medium supplemented with cryoprotectants like glycerol, ensuring stability and functionality upon thawing for experimental use.
What are the methods for quantifying Christensenella timonensis in experimental samples?
Quantification of Christensenella timonensis can be achieved through qPCR targeting specific genomic regions or through metagenomic sequencing methods, providing accurate assessment of its abundance in complex microbial communities.
How does Christensenella timonensis interact with host cells In vitro studies?
In vitro studies suggest that Christensenella timonensis may interact with intestinal epithelial cells and immune cells, influencing host immune responses and epithelial barrier function, pivotal for understanding its potential therapeutic applications.
What experimental models are suitable for studying Christensenella timonensis efficacy?
Animal models, such as germ-free mice colonized with Christensenella timonensis, provide valuable insights into its effects on gut microbiota composition, metabolic parameters, and potential therapeutic benefits in conditions like obesity and metabolic syndrome.
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