Christensenella is a Gram-negative, strictly anaerobic genus of bacteria first discovered in the human gut. Christensenella massiliensis was isolated from human stool specimen from a 66-year-old patient.
For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
Product Information | |
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Product Overview | Christensenella is a Gram-negative, strictly anaerobic genus of bacteria first discovered in the human gut. Christensenella massiliensis was isolated from human stool specimen from a 66-year-old patient. |
Target | Christensenella |
Genus | Christensenella |
Strain Designation | Marseille-P2438 |
Application | Study and research |
Culture Medium | RCM medium |
Culture Conditions | 37°C; Anaerobic |
Source | Human stool specimen from a 66-year-old patient |
Risk Group | 1 |
Genbank Accession Numbers | 16S rRNA gene: LT161898 |
Product Format | Freeze-dried |
Packaging | Ampoule tube |
Storage | -80°C |
Shelf Life | 6 years |
Target Introduction | |
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Introduction | Christensenella is a Gram-negative, non-spore-forming, anaerobic, and nonmotile genus from the family Christensenellaceae. Christensenella minuta, Christensenella timonensis, and Christensenella massiliensis are currently the only known species of Christensenella, all of which were isolated from human stool samples. Development of therapeutic applications for Christensenella is an area of active research. Bacteria of the Christensenellaceae family hold great potential for therapeutic use as live biotherapeutic products to treat obesity and associated metabolic disorders. The larger role of Christensenella in the gut microbiome has also been a focal point for understanding how it may relate to other diseases. |
Alternative Names | Christensenella massiliensis |
Christensenella massiliensis is a bacterial strain recognized for its potential implications in human health, particularly relating to obesity and metabolic syndromes. Researchers investigate its role in the gut microbiome to understand how it influences these conditions.
For culturing Christensenella massiliensis, researchers typically use anaerobic conditions with specific growth media that simulate the gut environment. This process requires precise temperature and pH settings to ensure viable and reproducible cultures.
When handling Christensenella massiliensis, it is essential to follow standard biosafety protocols applicable to anaerobic bacteria. These include using appropriate personal protective equipment and conducting experiments within a controlled environment like an anaerobic chamber.
Yes, Christensenella massiliensis can be genetically modified to study gene function and interaction with host cells. This is typically done using techniques like CRISPR/Cas9 to knock out or insert genes and analyze the effects on bacterial behavior and interaction with the host.
Results from studies on Christensenella massiliensis can lead to developing new treatments or dietary supplements aimed at modulating the gut microbiome to manage or prevent obesity and associated metabolic disorders. However, translational application requires thorough clinical trials to confirm efficacy and safety.
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For Research Use Only. Not intended for use in food manufacturing or medical procedures (diagnostics or therapeutics). Do Not Use in Humans.
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