Live Biotherapeutic Drug Discovery

Live Biotherapeutics Drug Discovery

Living biotherapeutic products (LBPs), as a kind of biological products, have broad application prospects in the prevention or treatment of metabolic diseases and pathogenic infections. The safety evaluation of LBPs needs further special consideration compared to traditional medicines, due to the peculiar biological properties and mode of action of the live microorgaisms that they contain.

LBPs have shown great promise for reducing infection

Next-Generation Probiotics (NGPs)

With the development of analytical methods, such as the next-generation sequencing and bioinformatics platforms, many potential NGPs have been discovered or currently under intensive development.

Diseases Linked to NGPs

Under healthy conditions, dynamic interactions exist between the host cells and the vast diversity of microbiota microbes to keep a balance. Once the situation of microbiota dysbiosis, lots of diseases will be developed.

Our Products

Fig.1. Probiotic powder. (Creative Biolabs Authorized)

Probiotic Ingredients

Probiotic Strains

Fig.3. Probiotic host strains. (Creative Biolabs Authorized)

Probiotic Expression Systems

Fig.4. Sterilizing indicator. (Creative Biolabs Authorized)

Biological Indicators

Fig.5 Quality control strain products. (Creative Biolabs Authorized)

QC Strains

Fig.6 DNA of probiotics. (Creative Biolabs Authorized)

Probiotic DNA Standards

Fig.7 Heat-inactivated quantitative probiotics. (Creative Biolabs Authorized)

Inactivated Probiotics

Recommended Resources

Fig.8 Probiotic for animal study. (Creative Biolabs Authorized)

Service Brochure - Custom lab-scale probiotic production

Fig.9 MIC test for different strains. (Creative Biolabs Authorized)

Service Brochure - Minimal Inhibitory Concentration (MIC) Test

Fig.10 Akkermansia muciniphila for in vivo study. (Creative Biolabs Original)

Case Study - Akkermansia muciniphila Lab-scale Production

Fig.11 Bacteroides vulgatus for in vivo study. (Creative Biolabs Original)

Case Study - Bacteroides vulgatus Lab-scale Production

Fig.12 Engineered EcN construction. (Creative Biolabs Authorized)

Case Study - Construction of Engineered E. coli Nissle 1917 (EcN) Strains

Fig.13 Engineered Lactococcus lacti construction. (Creative Biolabs Authorized)

CaseStudy - Lactococcus lactis NZ9000 Expression Strain

Fig.14 Cas study for MIC test. (Creative Biolabs Authorized)

Case Study - MIC Testing for API

Fig.15 Case study for bioburden testing. (Creative Biolabs Authorized)

Case Study - Microbial Stability Study of Non-sterile Oral Solution

Ready to Get Started?

Creative Biolabs has abundant experience in LBPs discovery to help our customers accelerate live biotherapeutics projects. We will work with you at all stages of the LBPs development process from the initiation of your project to the large-scale production of your microbes.

ISO 9001 Certified - Creative Biolabs Quality Management System.

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